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为什么要研究果蝇?开展低成本的公众参与活动,解释研究黑腹果蝇的基础生物医学研究的价值。

Why flies? Inexpensive public engagement exercises to explain the value of basic biomedical research on Drosophila melanogaster.

机构信息

Department of Zoology, University of Cambridge, United Kingdom.

出版信息

Adv Physiol Educ. 2011 Dec;35(4):384-92. doi: 10.1152/advan.00045.2011.

DOI:10.1152/advan.00045.2011
PMID:22139775
Abstract

Invertebrate model organisms are powerful systems for uncovering conserved principles of animal biology. Despite widespread use in scientific communities, invertebrate research is often severely undervalued by laypeople. Here, we present a set of simple, inexpensive public outreach exercises aimed at explaining to the public why basic research on one particular invertebrate, the insect Drosophila melanogaster, is valuable. First, we designed seven teaching modules that highlight cutting-edge research in Drosophila genetics, metabolism, physiology, and behavior. We then implemented these exercises in a public outreach event that included both children and adults. Quantitative evaluation of participant feedback suggests that these exercises 1) teach principles of animal biology, 2) help laypeople better understand why researchers study fruit flies, and 3) are effective over a wide range of age groups. Overall, this work provides a blueprint for how to use Drosophila as a vehicle for increasing public awareness and appreciation of basic research on genetically tractable insects in particular and invertebrates in general.

摘要

无脊椎动物模式生物是揭示动物生物学保守原理的强大系统。尽管在科学界得到了广泛应用,但无脊椎动物研究经常被外行人严重低估。在这里,我们提出了一系列简单、廉价的公众宣传活动,旨在向公众解释为什么对一种特定的无脊椎动物——昆虫黑腹果蝇进行基础研究是有价值的。首先,我们设计了七个教学模块,强调了果蝇遗传学、新陈代谢、生理学和行为方面的前沿研究。然后,我们在一个包括儿童和成人的公众宣传活动中实施了这些练习。对参与者反馈的定量评估表明,这些练习 1)教授动物生物学原理,2)帮助外行人更好地理解为什么研究人员研究果蝇,3)在广泛的年龄组中都很有效。总的来说,这项工作为如何利用果蝇作为增加公众对特别是遗传上易于研究的昆虫和无脊椎动物的基础研究的认识和欣赏提供了蓝图。

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Why flies? Inexpensive public engagement exercises to explain the value of basic biomedical research on Drosophila melanogaster.为什么要研究果蝇?开展低成本的公众参与活动,解释研究黑腹果蝇的基础生物医学研究的价值。
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引用本文的文献

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J Undergrad Neurosci Educ. 2018 Jun 15;16(2):A177-A185. eCollection 2018 Spring.
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Collective agency and the concept of 'public' in public involvement: A practice-oriented analysis.公共参与中的集体能动性与“公众”概念:一项基于实践的分析。
BMC Med Ethics. 2016 Jan 5;17:1. doi: 10.1186/s12910-015-0083-z.
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Spotting the differences: probing host/microbiota interactions with a dedicated software tool for the analysis of faecal outputs in Drosophila.
发现差异:使用专门的软件工具探究果蝇粪便输出,以深入研究宿主/微生物群的相互作用。
J Insect Physiol. 2014 Oct;69:126-35. doi: 10.1016/j.jinsphys.2014.05.023. Epub 2014 Jun 4.
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Electroretinograms in Drosophila: a robust and genetically accessible electrophysiological system for the undergraduate laboratory.果蝇的视网膜电图:一种适用于本科实验室的强大且可通过遗传学手段研究的电生理系统。
J Undergrad Neurosci Educ. 2012 Fall;11(1):A149-57. Epub 2012 Oct 15.
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The fundamentals of flying: simple and inexpensive strategies for employing Drosophila genetics in neuroscience teaching laboratories.飞行的基本原理:在神经科学教学实验室中运用果蝇遗传学的简单且经济的策略。
J Undergrad Neurosci Educ. 2012 Fall;11(1):A139-48. Epub 2012 Oct 15.
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How to design a genetic mating scheme: a basic training package for Drosophila genetics.如何设计遗传交配方案:果蝇遗传学基础培训包。
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