Matsukawa Y, Hatta Y, Shida M, Baba M, Sawada S, Horie T, Aizawa S, Amamiya Y
First Department of Internal Medicine, Nihon University School of Medicine.
Rinsho Ketsueki. 1990 Jun;31(6):858-9.
A 22-year-old female patient with severe aplastic anemia was treated by ATG.bolus methylprednisolone therapy. After the therapy, anemia and thrombocytopenia began to recover within a month. The frequency of blood transfusion decreased thereafter. Since anemia due to splenomegaly was certified, bolus methylprednisolone therapy was performed in good response. Suppressor T-cells towards hemopoiesis were confirmed in this case, and hemopoietic potential was augmented by ATG.bolus methylprednisolone therapy. In spite of discontinuation of any therapy in 1986, she is being in good health more than five years.
一名22岁患有严重再生障碍性贫血的女性患者接受了抗胸腺细胞球蛋白（ATG）和大剂量甲泼尼龙治疗。治疗后，贫血和血小板减少在一个月内开始恢复。此后输血频率降低。由于确诊为脾肿大所致贫血，遂进行大剂量甲泼尼龙治疗，效果良好。该病例中证实存在针对造血的抑制性T细胞，且通过ATG和大剂量甲泼尼龙治疗增强了造血潜能。尽管在1986年停止了所有治疗，但她至今已保持健康超过五年。
