Kikuchi K, Igarashi A, Ishibashi Y, Inokuma S, Takehara K
Department of Dermatology, Faculty of Medicine, Tokyo University.
Nihon Hifuka Gakkai Zasshi. 1990 May;100(6):695-700.
Analytical studies were performed on the respiratory symptoms in 31 systemic sclerosis cases. Respiratory symptoms were expressed by scores from 1) coughs, 2) difficulties in walking, 3) difficulties in ascending, 4) dyspnea . In early stage cases with slight clinical symptoms, %VC was always normal, but %DLco was generally reduced. Because of good correlation between respiratory functions and clinical symptom scores, it is available to use the scores as well as %DLLco and %VC to diagnose slight lung involvement in systemic sclerosis. Also the clinical symptom scores are related to the roentgenographic manifestations of lung fibrosis which are characteristic in systemic sclerosis. Therefore we felt that this system of clinical symptom scores was useful to follow-up the patients.
对31例系统性硬化症患者的呼吸系统症状进行了分析研究。呼吸系统症状通过以下方面的评分来表示:1)咳嗽,2)行走困难,3)上楼困难,4)呼吸困难。在临床症状轻微的早期病例中,肺活量百分比(%VC)通常正常,但一氧化碳弥散量百分比(%DLco)一般降低。由于呼吸功能与临床症状评分之间具有良好的相关性,因此可以使用这些评分以及%DLco和%VC来诊断系统性硬化症患者轻微的肺部受累情况。此外,临床症状评分与系统性硬化症特有的肺纤维化的影像学表现相关。因此,我们认为这种临床症状评分系统对患者的随访很有用。