Department of Medicine, Georgetown University Hospital, Washington, DC 20016, USA.
Am J Trop Med Hyg. 2011 Dec;85(6):1008-9. doi: 10.4269/ajtmh.2011.11-0412.
We describe a case of a woman who developed a peripheral polyneuropathy shortly after completing 4 weekly doses of mefloquine hydrochloride (250 mg) malaria prophylaxis. Although mefloquine-related central nervous system neuropathy is well described in the literature, peripheral polyneuropathy similar to this case has been documented only once before, to our knowledge.
我们描述了一例女性患者,在完成 4 剂每周的盐酸甲氟喹(250 毫克)疟疾预防用药后不久,出现周围性多发性神经病。尽管文献中已有充分描述与甲氟喹相关的中枢神经系统神经病,但据我们所知,类似本例的周围性多发性神经病仅以前有过一次记录。