Suppr超能文献

癌症恶病质

Cancer cachexia.

作者信息

Dhanapal Raghu, Saraswathi Tr, Govind Rajkumar N

机构信息

Department of Oral Pathology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.

出版信息

J Oral Maxillofac Pathol. 2011 Sep;15(3):257-60. doi: 10.4103/0973-029X.86670.

Abstract

Cancer cachexia is a wasting syndrome characterized by weight loss, anorexia, asthenia and anemia. The pathogenicity of this syndrome is multifactorial, due to a complex interaction of tumor and host factors. The signs and symptoms of cachexia are considered as the prognostic parameters in cancer patients. This review gives an emphasis on the various mechanisms involved in cachexia and an insight into head and neck cancer cachexia.

摘要

癌症恶病质是一种以体重减轻、厌食、乏力和贫血为特征的消耗综合征。由于肿瘤和宿主因素的复杂相互作用,该综合征的发病机制是多因素的。恶病质的体征和症状被视为癌症患者的预后参数。本综述重点介绍了恶病质涉及的各种机制,并深入探讨了头颈癌恶病质。

相似文献

1
Cancer cachexia.
J Oral Maxillofac Pathol. 2011 Sep;15(3):257-60. doi: 10.4103/0973-029X.86670.
2
Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia.
J Cachexia Sarcopenia Muscle. 2020 Jun;11(3):619-635. doi: 10.1002/jcsm.12528. Epub 2020 Mar 6.
3
Understanding Cachexia in Head and Neck Cancer.
Asia Pac J Oncol Nurs. 2021 Aug 27;8(5):527-538. doi: 10.4103/apjon.apjon-2145. eCollection 2021 Sep-Oct.
4
Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia.
Int J Biochem Cell Biol. 2005 May;37(5):1084-104. doi: 10.1016/j.biocel.2004.10.003. Epub 2004 Dec 30.
5
Cytokines and cancer anorexia cachexia syndrome.
Am J Hosp Palliat Care. 2008 Oct-Nov;25(5):407-11. doi: 10.1177/1049909108315518. Epub 2008 Apr 10.
6
Cancer cachexia syndrome in head and neck cancer patients: Part II. Pathophysiology.
Head Neck. 2007 May;29(5):497-507. doi: 10.1002/hed.20630.
7
Cancer anorexia - cachexia syndrome.
Acta Med Indones. 2012 Apr;44(2):154-62.
9
[The cachexia-anorexia syndrome among oncological patients].
Gac Med Mex. 2008 Sep-Oct;144(5):435-40.
10
[Pathogenesis and treatment of cancer anorexia-cachexia, with special emphasis on aged patients].
Nihon Ronen Igakkai Zasshi. 2004 Sep;41(5):460-7. doi: 10.3143/geriatrics.41.460.

引用本文的文献

1
Vagal blockade of the brain-liver axis deters cancer-associated cachexia.
Cell. 2025 Jul 29. doi: 10.1016/j.cell.2025.07.016.
2
Intramuscular CMT-167 Tumors Produce a Mild Cachexia Phenotype in C57BL/6J Mice.
JCSM Commun. 2025 Jan-Jun;8(1). doi: 10.1002/rco2.117. Epub 2025 Feb 6.
4
Metabolic interplays between the tumour and the host shape the tumour macroenvironment.
Nat Rev Cancer. 2025 Apr;25(4):274-292. doi: 10.1038/s41568-024-00786-4. Epub 2025 Jan 20.
5
Cell-death induced immune response and coagulopathy promote cachexia in .
bioRxiv. 2025 Feb 10:2025.01.07.631515. doi: 10.1101/2025.01.07.631515.
6
Updates on Methods for Body Composition Analysis: Implications for Clinical Practice.
Curr Obes Rep. 2025 Jan 11;14(1):8. doi: 10.1007/s13679-024-00593-w.
10
Brassinin alleviates cancer cachexia by suppressing diverse inflammatory mechanisms in mice.
MedComm (2020). 2024 May 28;5(6):e558. doi: 10.1002/mco2.558. eCollection 2024 Jun.

本文引用的文献

1
Cancer cachexia therapy: a key weapon in the fight against cancer.
Curr Opin Clin Nutr Metab Care. 2011 May;14(3):268-73. doi: 10.1097/MCO.0b013e3283455e21.
2
Hormonal regulators of appetite.
Int J Pediatr Endocrinol. 2009;2009:141753. doi: 10.1155/2009/141753. Epub 2008 Dec 3.
3
Mechanisms of cancer cachexia.
Physiol Rev. 2009 Apr;89(2):381-410. doi: 10.1152/physrev.00016.2008.
4
Refeeding syndrome--awareness, prevention and management.
Head Neck Oncol. 2009 Jan 26;1:4. doi: 10.1186/1758-3284-1-4.
5
Inflammatory burden and amino acid metabolism in cancer cachexia.
Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):72-7. doi: 10.1097/MCO.0b013e32831cef61.
6
Defining cancer cachexia in head and neck squamous cell carcinoma.
Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6561-7. doi: 10.1158/1078-0432.CCR-07-0116.
8
Mediators involved in the cancer anorexia-cachexia syndrome: past, present, and future.
Nutrition. 2005 Sep;21(9):977-85. doi: 10.1016/j.nut.2005.02.003.
9
Cancer anorexia-cachexia syndrome: cytokines and neuropeptides.
Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):427-34. doi: 10.1097/01.mco.0000134363.53782.cb.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验