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嗜铬细胞瘤的医学管理:内分泌科医生的作用。

Medical management of pheochromocytoma: Role of the endocrinologist.

作者信息

Garg M K, Kharb Sandeep, Brar K S, Gundgurthi Abhay, Mittal Rakesh

机构信息

Department of Endocrinology, Army Hospital (Research and Referral), Delhi Cantt, India.

出版信息

Indian J Endocrinol Metab. 2011 Oct;15 Suppl 4(Suppl4):S329-36. doi: 10.4103/2230-8210.86976.

Abstract

Pheochromocytoma is a rare tumor arising from chromaffin cells in adrenal medulla or other paraganglia in the body, which may be associated with many genetic syndromes and mutation. The role of endocrinologist is in biochemical diagnosis of suspected cases; its anatomic and functional localization with the help of imaging like CT, MRI, and nuclear scanning; preoperative control of hypertension; and postoperative follow-up of cases that have undergone surgical resection. Familial and genetic screening of cases and their family is important to detect occult cases. Endocrinologist will also play a role in cases with malignant pheochromocytoma in assessment of metastasis, control, chemoradiotherapy, and follow-up.

摘要

嗜铬细胞瘤是一种起源于肾上腺髓质或体内其他副神经节嗜铬细胞的罕见肿瘤,可能与许多遗传综合征和突变有关。内分泌科医生的职责包括对疑似病例进行生化诊断;借助CT、MRI和核扫描等影像学手段进行解剖和功能定位;术前控制高血压;以及对接受手术切除的病例进行术后随访。对病例及其家族进行家族性和基因筛查对于发现隐匿性病例很重要。内分泌科医生在恶性嗜铬细胞瘤病例的转移评估、控制、放化疗及随访中也将发挥作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee47/3230088/9c7a44816bb4/IJEM-15-329-g003.jpg

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