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[急诊医疗服务重症监护病房患者血液分离株的抗生素敏感性]

[Antibiotic susceptibility of isolates from blood of patients in intensive care units of emergency medical service].

作者信息

Chernen'kaia T V, Borisova L A, Vorob'eva T Iu, Aleksandrova I V, Kosolapov D A

出版信息

Antibiot Khimioter. 2011;56(5-6):30-6.

PMID:22145228
Abstract

The microbiological tests of 769 blood samples from 220 patients, treated in 4 intensive care units of the N.V. Sklifosovsky Research Institute for Emergency Medical Service within a period from January 2009 to June 2010, were analysed. Etiologically significant microorganisms were detected in 323 samples (42%). 253 isolates were used in the analysis. Grampositive and gramnegative pathogens were detected in 47 and 42% of the cases respectively. Candida and anaerobic organisms were isolated in 8 and 3% of the cases respectively. Staphylococcus aureus and enterococci were isolated in 24 and 15% of the cases respectively. Nonfermenting gramnegative bacteria and enterobacteria were revealed in 25 and 17% of the cases respectively. Differences in the spectrum of the sepsis pathogens depending on the patients contingent were shown. The maximum summary susceptibility of the grampositive cocci was observed with respect to vancomycin and linezolid and that of the gramnegative bacteria was stated with respect to imipenem and meropenem.

摘要

对2009年1月至2010年6月期间在N.V.斯克利福索夫斯基急救医学研究所4个重症监护病房接受治疗的220名患者的769份血样进行了微生物学检测分析。在323份样本(42%)中检测到具有病因学意义的微生物。分析使用了253株分离菌。革兰氏阳性菌和革兰氏阴性菌病原体分别在47%和42%的病例中被检测到。念珠菌和厌氧菌分别在8%和3%的病例中被分离出来。金黄色葡萄球菌和肠球菌分别在24%和15%的病例中被分离出来。非发酵革兰氏阴性菌和肠杆菌分别在25%和17%的病例中被发现。显示了败血症病原体谱因患者群体而异。观察到革兰氏阳性球菌对万古霉素和利奈唑胺的总体敏感性最高,革兰氏阴性菌对亚胺培南和美罗培南的总体敏感性最高。

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