Saha Abhijeet, Bagri Narendra, Mehera Neha, Dubey Nand Kishore, Batra Vinita
Division of Pediatric Nephrology, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, India.
J Pediatr Endocrinol Metab. 2011;24(9-10):789-92. doi: 10.1515/jpem.2011.372.
We present a rare case of membranoproliferative glomerulonephritis (MPGN) associated with autoimmune hypothyroidism in a child. The exact pathogenesis of glomerulonephritis remains unclear. Thyroxine replacement therapy along with steroids may lead to significant decrease in proteinuria and resolution of edema. Thyroid status should be evaluated in all cases with MPGN.
我们报告了一例儿童膜增生性肾小球肾炎（MPGN）合并自身免疫性甲状腺功能减退的罕见病例。肾小球肾炎的确切发病机制尚不清楚。甲状腺素替代疗法联合类固醇可能会导致蛋白尿显著减少和水肿消退。对于所有MPGN病例，均应评估甲状腺状态。
