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患有 ADHD 且伴有或不伴有共患阅读障碍的儿童的患者特征、合并症和药物使用情况:一项回顾性队列研究。

Patient characteristics, comorbidities, and medication use for children with ADHD with and without a co-occurring reading disorder: A retrospective cohort study.

机构信息

Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285 USA.

出版信息

Child Adolesc Psychiatry Ment Health. 2011 Dec 6;5:38. doi: 10.1186/1753-2000-5-38.

Abstract

BACKGROUND

Children and adolescents with attention-deficit/hyperactivity disorder (ADHD) often have a co-occurring reading disorder (RD). The purpose of this research was to assess differences between children with ADHD without RD (ADHD-only) and those with ADHD and co-occurring RD (ADHD+RD).

METHODS

Using data from the U.S. Thomson Reuter Marketscan® Databases for the years 2005 through 2007, this analysis compared the medical records--including patient demographics, comorbidities, and medication use--of children (age < 18) with ADHD-only to those with ADHD+RD.

RESULTS

Patients with ADHD+RD were significantly younger, more likely to have received a procedure code associated with formal psychological or non-psychological testing, and more likely to have been diagnosed with comorbid bipolar disorder, conduct disorder, or depression. They were no more likely to have received an antidepressant, anti-manic (bipolar), or antipsychotic, and were significantly less likely to have received a prescription for a stimulant medication.

CONCLUSIONS

Relying on a claims database, there appear to be differences in the patient characteristics, comorbidities, and medication use when comparing children with ADHD-only to those with ADHD+RD.

摘要

背景

患有注意力缺陷/多动障碍(ADHD)的儿童和青少年通常伴有共患的阅读障碍(RD)。本研究的目的是评估无 RD 的 ADHD 儿童(ADHD 仅有)与共患 RD 的 ADHD 儿童(ADHD+RD)之间的差异。

方法

利用 2005 年至 2007 年美国汤姆森路透市场扫描数据库的数据,本分析比较了 ADHD 仅有和 ADHD+RD 儿童的医疗记录,包括患者人口统计学、合并症和药物使用情况。

结果

ADHD+RD 患者明显更年轻,更有可能接受与正式心理或非心理测试相关的程序编码,并且更有可能被诊断为共患双相情感障碍、品行障碍或抑郁症。他们服用抗抑郁药、抗躁狂(双相)或抗精神病药的可能性没有增加,服用兴奋剂药物的可能性明显降低。

结论

依靠索赔数据库,在比较 ADHD 仅有和 ADHD+RD 儿童时,患者特征、合并症和药物使用情况似乎存在差异。

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