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性别差异与下腰痛和代谢综合征的关联:磐城队列研究(LOHAS)中的运动障碍综合征与健康结局。

Gender difference in association between low back pain and metabolic syndrome: locomotive syndrome and health outcome in Aizu cohort study (LOHAS).

机构信息

Department of Community Health Sciences, Kobe University Graduate School of Health Sciences, Kobe, Japan.

出版信息

Spine (Phila Pa 1976). 2012 Jun 1;37(13):1130-7. doi: 10.1097/BRS.0b013e31824231b8.

DOI:10.1097/BRS.0b013e31824231b8
PMID:22146290
Abstract

STUDY DESIGN

Cross-sectional survey. OBJECTIVE.: To investigate the relationship between low back pain (LBP) and metabolic syndrome (Mets) in community-based Japanese subjects. SUMMARY OF BACKGROUND DATA.: Relatively few reports have demonstrated a relationship between general pain and Mets, and none have addressed the relationship between LBP and Mets.

METHODS

This study enrolled 2650 people from among residents aged 40 to 74 years in Tadami and Minamiaizu, Fukushima, Japan, who participated in health checkups conducted in 2008. LBP was defined as lower back pain continuing for more than 24 hours and severe enough to merit treatment, or it was based on clinical prediction rules from the clinical diagnosis support tool to identify patients with lumbar spinal stenosis. Mets was defined according to the Japanese criteria recommended by the Japanese Society of Internal Medicine. Prevalence of Mets was recorded for subjects with and without LBP. The relationship between LBP and Mets was investigated, using a generalized linear model. With LBP as the main explanatory variable and Mets as the outcome variable, risk ratios of Mets were calculated for men and women.

RESULTS

In this study, we analyzed a total of 1395 subjects. In men, the prevalence of Mets was 21.2% in those without LBP and 24.7% in those with LBP. In women, the prevalence of Mets was 12.4% in those without LBP and 23.7% in those with LBP. After adjusting for factors such as age, body mass index, occupational status, SF-36 mental health, and physical activity level, no relationship was noted between LBP and Mets in men. However, in women, the risk ratio for Mets in subjects with LBP compared with those without LBP was 1.5 (95% confidence interval, 1.0-2.1).

CONCLUSION

We observed a tendency toward higher prevalence of Mets among those with LBP than among those without it in women, but not in men.

摘要

研究设计

横断面调查。

目的

探讨社区日本人群中腰痛(LBP)与代谢综合征(Mets)的关系。

背景资料概要

相对较少的报告表明一般疼痛与 Mets 之间存在关系,并且没有研究涉及 LBP 与 Mets 之间的关系。

方法

本研究纳入了 2650 名来自日本福岛县磐城市和南相马市年龄在 40 至 74 岁之间的居民,他们参加了 2008 年进行的健康检查。腰痛定义为持续 24 小时以上且需要治疗的下背部疼痛,或根据临床诊断支持工具中的临床预测规则来识别腰椎管狭窄症患者。Mets 根据日本内科协会推荐的日本标准进行定义。记录有和无 LBP 的受试者中 Mets 的患病率。使用广义线性模型研究 LBP 和 Mets 之间的关系。以 LBP 为主要解释变量,以 Mets 为结局变量,计算男性和女性 Mets 的风险比。

结果

在这项研究中,我们共分析了 1395 名受试者。在男性中,无 LBP 的受试者 Mets 的患病率为 21.2%,有 LBP 的受试者 Mets 的患病率为 24.7%。在女性中,无 LBP 的受试者 Mets 的患病率为 12.4%,有 LBP 的受试者 Mets 的患病率为 23.7%。在校正年龄、体重指数、职业状况、SF-36 心理健康和体力活动水平等因素后,男性中 LBP 与 Mets 之间没有关系。然而,在女性中,与无 LBP 的受试者相比,有 LBP 的受试者 Mets 的风险比为 1.5(95%置信区间,1.0-2.1)。

结论

我们观察到女性中 LBP 受试者 Mets 的患病率较无 LBP 的受试者更高,但男性中则无此趋势。

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