Shishkin A N, Shulutko B I, Budaĭ O P, Kolmakova E V
Klin Med (Mosk). 1990 Jun;68(6):58-61.
The results are available of combined examination of the kidneys in 84 patients with manifest nephrotic syndrome varying in etiology: 57 had glomerulonephritis, 18 amyloidosis, 9 diabetic nephropathy. The study covered lipid metabolism, immunological status, lifetime morphological investigation of the kidneys. The latter procedure proved advantageous over biochemical and immunological studies in deciding upon nosological diagnosis of nephrotic syndrome and its prognosis. Destruction of podocytic miner processes revealed in all the syndrome cases can serve a uniform morphological substrate underlying massive proteinuria.
对84例病因各异的显性肾病综合征患者的肾脏进行联合检查的结果如下：57例患有肾小球肾炎，18例患有淀粉样变性，9例患有糖尿病肾病。该研究涵盖了脂质代谢、免疫状态以及肾脏的终生形态学研究。在确定肾病综合征的病因诊断及其预后方面，后一程序被证明比生化和免疫学研究更具优势。在所有综合征病例中均发现的足细胞微绒毛破坏可作为大量蛋白尿的统一形态学基础。
