[Effect of therapeutic plasmapheresis on the system of hemostasis in patients with chronic glomerulonephritis].

Coagulative and thrombocytic hemostasis as well as the fibrinolytic system were studied in 20 patients with chronic glomerulonephritis on plasmapheresis (PA). It is shown that PA promotes activation of platelet aggregation which can be related to their contact activation. Coagulation enhances, antithrombic potential reduces, fibrinogen is mechanically removed as well as fibrin-monomer soluble complexes, fibrin degradation products. In view of the importance of the fibrinolytic system in chronic glomerulonephritis, measures should be taken to correct the disturbances detected.