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[高压氧疗的细胞遗传学效应]

[Cytogenetic effects of hyperbaric oxygenation].

作者信息

Gus'kov E P, Shkurat T P, Shimanskaia E I, Ianushevich S V, Nikolaeva E E

出版信息

Kosm Biol Aviakosm Med. 1990 Jul-Aug;24(4):48-52.

PMID:2214668
Abstract

This paper presents cytogenetic data obtained from peripheral blood of patients who were treated with hyperbaric oxygenation (HBO) at 0.15-0.2 MPa for 40 min daily during 10 days. The patients showed a significant increase of chromosome aberrations mainly caused by chromatid and chromosome breaks. The level of induced aberrations showed individual variations. These results suggest that HBO may have an indirect effect on the genetic apparatus of human somatic cells.

摘要

本文呈现了从患者外周血中获取的细胞遗传学数据,这些患者在10天内每天接受0.15 - 0.2兆帕的高压氧治疗(HBO)40分钟。患者出现了主要由染色单体和染色体断裂导致的染色体畸变显著增加。诱导畸变水平存在个体差异。这些结果表明高压氧治疗可能对人体体细胞的遗传机制有间接影响。

相似文献

1
[Cytogenetic effects of hyperbaric oxygenation].[高压氧疗的细胞遗传学效应]
Kosm Biol Aviakosm Med. 1990 Jul-Aug;24(4):48-52.
2
Genetic effects of hyperbaric oxygen therapy.
Mutat Res. 1990 Aug;241(4):341-7. doi: 10.1016/0165-1218(90)90063-8.
3
[Predicting the genome response of the somatic cells of divers to hyperoxic medium].[预测潜水员体细胞对高氧介质的基因组反应]
Fiziol Zh (1978). 1991 Jul-Aug;37(4):119-23.
4
[Cytogenetic consequences of hyperbaric oxygenation in the sequence of cell cycles of human peripheral blood lymphocytes].[高压氧对人外周血淋巴细胞细胞周期序列的细胞遗传学影响]
Genetika. 1985 Aug;21(8):1361-7.
5
[The effect of hyperbaric oxygenation on rat somatic and generative cells].
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[The cytogenetic action of antilymphocyte globulin on the lymphocytes of bronchial asthma patients].
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[Decrease of incidence of chromosome aberrations after a course of hyperbaric oxygenation].[高压氧治疗疗程后染色体畸变发生率的降低]
Biull Eksp Biol Med. 1991 May;111(5):532-4.
8
[Cytogenetic after-effects of fractionated and prolonged exposure to hyperbaric oxygenation].[分次长时间高压氧暴露的细胞遗传学后遗症]
Genetika. 1985 Oct;21(10):1693-9.
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[Changes in the fatty acid content of the erythrocytes in peptic ulcer patients during hyperbaric oxygenation].[高压氧治疗期间消化性溃疡患者红细胞脂肪酸含量的变化]
Vrach Delo. 1986 Aug(8):80-2.
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Increased sensitivity to mitomycin C-induced sister chromatid exchange in lymphocytes from patients undergoing hyperbaric oxygen therapy.接受高压氧治疗患者的淋巴细胞对丝裂霉素C诱导的姐妹染色单体交换敏感性增加。
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