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Postglucose growth hormone nadir and insulin-like growth factor-1 in naïve-active acromegalic patients: do these parameters always correlate?

作者信息

Ribeiro-Oliveira Antônio, Faje Alex, Barkan Ariel

机构信息

Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

Arq Bras Endocrinol Metabol. 2011 Oct;55(7):494-7. doi: 10.1590/s0004-27302011000700011.

DOI:10.1590/s0004-27302011000700011
PMID:22147100
Abstract
摘要

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Postglucose growth hormone nadir and insulin-like growth factor-1 in naïve-active acromegalic patients: do these parameters always correlate?初发活动性肢端肥大症患者葡萄糖负荷后生长激素最低点及胰岛素样生长因子-1：这些参数总是相关吗？
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2
Assessment of disease activity in treated acromegalic patients using a sensitive GH assay: should we achieve strict normal GH levels for a biochemical cure?使用灵敏的生长激素检测法评估经治疗的肢端肥大症患者的疾病活动度：生化治愈是否应达到严格的正常生长激素水平？
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3
Assessment of disease activity in acromegaly by means of a single blood sample: comparison of the 120th minute postglucose value with spontaneous GH secretion and with the IGF system.通过单次血样评估肢端肥大症的疾病活动：葡萄糖负荷后120分钟值与自发性生长激素分泌及胰岛素样生长因子系统的比较
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Value of early postoperative random growth hormone levels and nadir growth hormone levels after oral glucose tolerance testing in acromegaly.肢端肥大症患者术后早期随机生长激素水平及口服葡萄糖耐量试验后生长激素最低点水平的价值
Growth Horm IGF Res. 2018 Aug;41:64-70. doi: 10.1016/j.ghir.2018.03.002. Epub 2018 Mar 8.
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Usefulness of different biochemical markers of the insulin-like growth factor (IGF) family in diagnosing growth hormone excess and deficiency in adults.胰岛素样生长因子（IGF）家族不同生化标志物在诊断成人生长激素过多和缺乏中的应用价值。
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Diagnostic value of the acid-labile subunit in acromegaly: evaluation in comparison with insulin-like growth factor (IGF) I, and IGF-binding protein-1, -2, and -3.酸性不稳定亚基在肢端肥大症中的诊断价值：与胰岛素样生长因子（IGF）I、IGF结合蛋白-1、-2和-3对比评估
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The effects of long-term growth hormone and insulin-like growth factor-1 exposure on the development of cardiovascular, cerebrovascular and metabolic co-morbidities in treated patients with acromegaly.长期生长激素和胰岛素样生长因子-1 暴露对肢端肥大症治疗患者心血管、脑血管和代谢合并症发展的影响。
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Diagnostic value of serum IGF-I and IGFBP-3 in growth hormone disorders in adults.血清胰岛素样生长因子-I（IGF-I）和胰岛素样生长因子结合蛋白-3（IGFBP-3）在成人生长激素紊乱中的诊断价值
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J Clin Endocrinol Metab. 2021 Jul 13;106(8):e2887-e2899. doi: 10.1210/clinem/dgab257.
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Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels-A Randomized, Double-Blind, Placebo-Controlled Trial.含胶原蛋白肽和鸟氨酸的复合补充剂对皮肤状况和血浆 IGF-1 水平的影响：一项随机、双盲、安慰剂对照试验。
Mar Drugs. 2018 Dec 3;16(12):482. doi: 10.3390/md16120482.
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Growth hormone: isoforms, clinical aspects and assays interference.
生长激素：异构体、临床方面及检测干扰
Clin Diabetes Endocrinol. 2018 Aug 28;4:18. doi: 10.1186/s40842-018-0068-1. eCollection 2018.
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Diagnosis of acromegaly: black, white… and sometimes gray!肢端肥大症的诊断：非黑即白……有时也会模棱两可！
Arch Endocrinol Metab. 2016 Nov-Dec;60(6):505-506. doi: 10.1590/2359-3997000000231.
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Multiple facets in the control of acromegaly.肢端肥大症控制的多个方面
Pituitary. 2014 Jan;17 Suppl 1(Suppl 1):S11-7. doi: 10.1007/s11102-013-0536-7.
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The changing face of acromegaly--advances in diagnosis and treatment.肢端肥大症的变化面貌——诊断和治疗的进展。
Nat Rev Endocrinol. 2012 Oct;8(10):605-11. doi: 10.1038/nrendo.2012.101. Epub 2012 Jun 26.