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本文引用的文献

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2011 ACCF/AHA focused update of the Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (updating the 2007 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the American College of Emergency Physicians, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.2011年美国心脏病学会基金会/美国心脏协会《不稳定型心绞痛/非ST段抬高型心肌梗死患者管理指南》重点更新版（更新2007年指南）：美国心脏病学会基金会/美国心脏协会实践指南工作组报告，该工作组与美国急诊医师学会、心血管造影和介入学会以及胸外科医师学会合作制定。
J Am Coll Cardiol. 2011 May 10;57(19):1920-59. doi: 10.1016/j.jacc.2011.02.009. Epub 2011 Mar 28.
2
ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents.美国心脏病学会基金会/美国胃肠病学会/美国心脏协会2010年质子泵抑制剂与噻吩并吡啶类药物联合使用专家共识文件：ACCF/ACG/AHA 2008年关于降低抗血小板治疗和非甾体抗炎药使用的胃肠道风险专家共识文件的重点更新。美国心脏病学会基金会专家共识文件特别工作组报告。
J Am Coll Cardiol. 2010 Dec 7;56(24):2051-66. doi: 10.1016/j.jacc.2010.09.010.
3
Clopidogrel with or without omeprazole in coronary artery disease.氯吡格雷联合或不联合奥美拉唑用于冠心病。
N Engl J Med. 2010 Nov 11;363(20):1909-17. doi: 10.1056/NEJMoa1007964. Epub 2010 Oct 6.
4
Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.氯吡格雷和阿司匹林在急性冠脉综合征中的剂量比较。
N Engl J Med. 2010 Sep 2;363(10):930-42. doi: 10.1056/NEJMoa0909475.
5
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial.急性冠状动脉综合征患者行经皮冠状动脉介入治疗时的双联（氯吡格雷标准剂量与双倍剂量和阿司匹林低剂量与高剂量）治疗（CURRENT-OASIS 7）：一项随机析因试验。
Lancet. 2010 Oct 9;376(9748):1233-43. doi: 10.1016/S0140-6736(10)61088-4.
6
Low-dose vs standard-dose unfractionated heparin for percutaneous coronary intervention in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 randomized trial.低剂量与标准剂量未分馏肝素在急性冠脉综合征患者经磺达肝癸钠治疗中应用于经皮冠状动脉介入治疗的比较：FUTURA/OASIS-8 随机试验。
JAMA. 2010 Sep 22;304(12):1339-49. doi: 10.1001/jama.2010.1320. Epub 2010 Aug 31.
7
ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons.美国心脏病学会基金会/美国心脏协会氯吡格雷临床警报：针对美国食品药品监督管理局“黑框警告”的应对措施：美国心脏病学会基金会临床专家共识文件特别工作组及美国心脏协会报告，得到心血管造影和介入学会以及胸外科医师学会认可。
J Am Coll Cardiol. 2010 Jul 20;56(4):321-41. doi: 10.1016/j.jacc.2010.05.013.
8
Use of evidence-based therapies in short-term outcomes of ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in patients with chronic kidney disease: a report from the National Cardiovascular Data Acute Coronary Treatment and Intervention Outcomes Network registry.在慢性肾脏病患者中，基于证据的治疗方法在 ST 段抬高型心肌梗死和非 ST 段抬高型心肌梗死的短期结局中的应用：来自全国心血管数据急性冠状动脉治疗和干预结局网络注册的报告。
Circulation. 2010 Jan 26;121(3):357-65. doi: 10.1161/CIRCULATIONAHA.109.865352. Epub 2010 Jan 11.
9
2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.2009年重点更新：美国心脏病学会/美国心脏协会ST段抬高型心肌梗死患者管理指南（更新2004年指南和2007年重点更新内容）以及美国心脏病学会/美国心脏协会/心血管造影和介入学会经皮冠状动脉介入治疗指南（更新2005年指南和2007年重点更新内容）——美国心脏病学会基金会/美国心脏协会实践指南工作组报告
J Am Coll Cardiol. 2009 Dec 1;54(23):2205-41. doi: 10.1016/j.jacc.2009.10.015.
10
Immediate vs delayed intervention for acute coronary syndromes: a randomized clinical trial.急性冠状动脉综合征的即时干预与延迟干预：一项随机临床试验。
JAMA. 2009 Sep 2;302(9):947-54. doi: 10.1001/jama.2009.1267.

2011 ACCF/AHA 不稳定型心绞痛/非 ST 段抬高型心肌梗死患者管理指南的重点更新（更新 2007 年指南）：临床医生重点关注

2011 ACCF/AHA focused update of the guidelines for the management of patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (updating the 2007 Guideline): highlights for the clinician.

机构信息

Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Clin Cardiol. 2012 Jan;35(1):3-8. doi: 10.1002/clc.20964. Epub 2011 Dec 6.

DOI:10.1002/clc.20964
PMID:22147672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6652446/
Abstract

The 2011 Update to the Unstable Angina/Non-ST-Elevation Myocardial Infarction (UA/NSTEMI) Guideline is based in evolving data or expert opinion and incorporates information from late-breaking clinical trials presented at the 2008-2009 Scientific Sessions of the American College of Cardiology, the American Heart Association, and the European Society of Cardiology, among others, as well as selected data through April 2010. The 5 key issues highlighted in this summary are: (1) the timing of acute interventional therapy in non-ST-elevation myocardial infarction; (2) emphasis on the timing, duration, and application of dual and triple antiplatelet therapy; (3) specific recommendations for patients with diabetes mellitus; (4) the role and potential benefit of invasive therapy in patients with advanced renal dysfunction; and (5) issues of quality improvement for acute coronary syndromes.

摘要

2011 年不稳定型心绞痛/非 ST 段抬高型心肌梗死（UA/NSTEMI）指南更新版基于不断发展的数据或专家意见，并纳入了美国心脏病学会 2008-2009 年科学会议、美国心脏协会和欧洲心脏病学会等机构的最新临床试验信息，以及截至 2010 年 4 月的其他选定数据。本摘要重点强调了 5 个关键问题：（1）非 ST 段抬高型心肌梗死患者急性介入治疗的时机；（2）强调双重和三重抗血小板治疗的时机、持续时间和应用；（3）对糖尿病患者的具体建议；（4）在肾功能严重受损患者中采用有创治疗的作用和潜在获益；（5）急性冠状动脉综合征的质量改进问题。