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Counterpoint: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? No.

作者信息

Rivers Emanuel P, Elkin Ronald, Cannon Chad M

机构信息

Department of Emergency Medicine and Surgery, Henry Ford Hospital, Wayne State University, Detroit, MI.

Department of Medicine, Pulmonary and Critical Care Medicine, California Pacific Medical Center, San Francisco, CA.

出版信息

Chest. 2011 Dec;140(6):1408-1413. doi: 10.1378/chest.11-2563.

Abstract
摘要

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本文引用的文献

1
Prevalence and characteristics of nonlactate and lactate expressors in septic shock.
J Crit Care. 2012 Aug;27(4):344-50. doi: 10.1016/j.jcrc.2012.01.005. Epub 2012 Mar 21.
2
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?
J Crit Care. 2011 Aug;26(4):435.e9-14. doi: 10.1016/j.jcrc.2010.09.007. Epub 2010 Dec 3.
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Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
Crit Care Med. 2008 Jan;36(1):296-327. doi: 10.1097/01.CCM.0000298158.12101.41.
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The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock.
Crit Care Med. 2007 Sep;35(9):2016-24. doi: 10.1097/01.ccm.0000281637.08984.6e.
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Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
Crit Care Med. 2004 Aug;32(8):1637-42. doi: 10.1097/01.ccm.0000132904.35713.a7.

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