Jang Eun Joo, Lee Ji Yeoun, Yoon Tae Young
Department of Dermatology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea.
Ann Dermatol. 2011 Nov;23(4):490-2. doi: 10.5021/ad.2011.23.4.490. Epub 2011 Nov 3.
Milia-like idiopathic calcinosis cutis (MICC) is characterized by smooth, firm, whitish papules resembling milia. Histologically, it appears as a well-defined, round, basophilic nodule within the upper dermis. Although the etiology and treatment remain unclear, it may resolve spontaneously. Some cases have been associated with Down syndrome, and the mean age of MICC patients was 9.9 years old. Herein, we report a rare case of MICC that was not associated with Down syndrome. Noticeably, the patient, a toddler, was born as a premature baby and had an ischemic injury on the right foot at birth. However, the lesions appeared on both feet, including the non-injured left foot. Otherwise he was healthy. After a 21-month follow-up period, the lesions had almost disappeared without any treatment.
粟丘疹样特发性皮肤钙化病(MICC)的特征是出现类似粟丘疹的光滑、坚实、白色丘疹。组织学上,它表现为真皮上层一个边界清晰、圆形的嗜碱性结节。尽管病因和治疗方法仍不明确,但它可能会自发消退。一些病例与唐氏综合征有关,MICC患者的平均年龄为9.9岁。在此,我们报告一例罕见的与唐氏综合征无关的MICC病例。值得注意的是,该患者为一名幼儿,系早产儿,出生时右脚有缺血性损伤。然而,皮损出现在双脚,包括未受伤的左脚。除此之外,他身体健康。经过21个月的随访期,皮损几乎未经任何治疗就已消失。