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良性头部组织细胞增多症:一例报告

Benign cephalic histiocytosis: a case report.

作者信息

Koca Rafet, Bektaş Sibel, Altinyazar H Cevdet, Sezer Tuna

机构信息

Department of Dermatology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey.

出版信息

Ann Dermatol. 2011 Nov;23(4):508-11. doi: 10.5021/ad.2011.23.4.508. Epub 2011 Nov 3.

DOI:10.5021/ad.2011.23.4.508
PMID:22148022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3229948/
Abstract

Histiocytic skin disorders are usually classified as either Langerhans' cell histiocytosis (LCH) or non LCH, based on the pathology. Benign cephalic histiocytosis (BCH) is a rare type of non-Langerhans histiocytitic disorder and is characterized by self-healing multiple small eruptions of yellow to red-brown papules on the face and upper trunk. Histologic features of this disorder show dermal proliferation of histiocytes that have intracytoplasmic comma-shaped bodies, coated vesicles and desmosome-like structures. In this study, we report on a 7-month-old boy who contained small yellow-red papules on his face that spread to his upper trunk. The clinical and histologic features in this patient were consistent with BCH.

摘要

组织细胞性皮肤病通常根据病理分为朗格汉斯细胞组织细胞增生症(LCH)或非LCH。良性头部组织细胞增生症(BCH)是一种罕见的非朗格汉斯组织细胞性疾病,其特征是面部和上躯干出现可自愈的多个黄色至红棕色丘疹的小皮疹。该疾病的组织学特征显示组织细胞在真皮层增殖,这些组织细胞具有胞浆内逗号形小体、包被小泡和桥粒样结构。在本研究中,我们报告了一名7个月大的男孩,其面部有小黄红色丘疹,并蔓延至上躯干。该患者的临床和组织学特征与BCH一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/aa90c23fbd73/ad-23-508-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/7723d6ee17a3/ad-23-508-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/680ae09f3da1/ad-23-508-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/dede9b243d8f/ad-23-508-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/aa90c23fbd73/ad-23-508-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/7723d6ee17a3/ad-23-508-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/680ae09f3da1/ad-23-508-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/dede9b243d8f/ad-23-508-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d840/3229948/aa90c23fbd73/ad-23-508-g004.jpg

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本文引用的文献

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2
Benign cephalic histiocytosis preceding the development of insulin-dependent diabetes mellitus.
Pediatr Dermatol. 2006 Jan-Feb;23(1):101-2. doi: 10.1111/j.1525-1470.2006.00187.x.
3
Benign cephalic histiocytosis in a British-African child.一名英裔非洲儿童的良性头部组织细胞增多症
Pediatr Dermatol. 2005 Sep-Oct;22(5):444-6. doi: 10.1111/j.1525-1470.2005.113.x.
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两例儿童病例中局部应用雷帕霉素成功治疗非朗格汉斯细胞组织细胞增多症
Clin Cosmet Investig Dermatol. 2022 Aug 6;15:1575-1582. doi: 10.2147/CCID.S375995. eCollection 2022.
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Benign cephalic histiocytosis.良性头部组织细胞增多症
Indian Dermatol Online J. 2013 Oct;4(4):300-1. doi: 10.4103/2229-5178.120646.
Is disseminated juvenile xanthogranulomatosis benign cephalic histiocytosis?播散性幼年黄色肉芽肿是良性头部组织细胞增多症吗?
Pediatr Dermatol. 2005 Jan-Feb;22(1):40-3. doi: 10.1111/j.1525-1470.2005.22109.x.
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7
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