Weston W L, Travers S H, Mierau G W, Heasley D, Fitzpatrick J
Departments of Dermatology and Pediatrics, University of Colorado School of Medicine, and Department of Pathology, Children's Hospital, Denver, Denver, Colorado, USA.
Pediatr Dermatol. 2000 Jul-Aug;17(4):296-8. doi: 10.1046/j.1525-1470.2000.01779.x.
Benign cephalic histiocytosis is a rare skin condition consisting of small tan papules on the face and upper trunk that is believed not to be associated with internal organ involvement. The infiltrating histiocytes are not Langerhans' cells (LCs). We report a 5-year-old girl who presented with diabetes insipidus 1 year after developing multiple small brown asymptomatic skin papules. Histologic examination revealed a non-LC histiocytic proliferation in the dermis without epidermal invasion. She had infiltration of the pituitary stalk on brain imaging. Diabetes insipidus has heretofore been associated with LC histiocytosis and xanthoma disseminatum but not benign cephalic histiocytosis.
良性头部组织细胞增多症是一种罕见的皮肤病，表现为面部和上躯干出现小的棕褐色丘疹，据信与内脏器官受累无关。浸润的组织细胞不是朗格汉斯细胞（LCs）。我们报告一名5岁女孩，在出现多个小的褐色无症状皮肤丘疹1年后出现尿崩症。组织学检查显示真皮内有非LC组织细胞增生，无表皮侵犯。脑部影像学检查发现她的垂体柄有浸润。尿崩症迄今为止一直与LC组织细胞增多症和播散性黄瘤有关，但与良性头部组织细胞增多症无关。
