Song Byong Han, Youn Sung Hwan, Park Eun Joo, Kwon In Ho, Kim Kwang Ho, Kim Kwang Joong
Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Ann Dermatol. 2011 Oct;23(Suppl 2):S250-3. doi: 10.5021/ad.2011.23.S2.S250. Epub 2011 Oct 31.
Sinusoidal hemangioma is a distinctive subset of a group of lesions known collectively as cavernous hemangiomas. Clinically, it develops in adults, predominantly females, and presents as a solitary, painless, bluish, deep dermal or subcutaneous nodule. Lipoma is the most common benign soft tissue tumor. Lipoma is distinguished from sinusoidal hemangioma on both clinical and histological grounds. Several studies have suggested that adipocytes originate from perivascular cells during adipogenesis. Angiogenic cytokines released by adipocytes play a role in the vasoproliferative response. The rearrangement or loss of chromosome 13 can also be associated with hemangioma. However, no previous cases of sinusoidal hemangioma have been associated with benign tumors like lipoma. Here, we describe an unusual case of sinusoidal hemangioma that occurred together with a lipoma on the right upper arm of a 43-year-old male.
窦性血管瘤是一组统称为海绵状血管瘤的病变中的一个独特子集。临床上，它在成年人中发病，以女性为主，表现为单个、无痛、蓝色、深部真皮或皮下结节。脂肪瘤是最常见的良性软组织肿瘤。脂肪瘤在临床和组织学上都与窦性血管瘤不同。几项研究表明，脂肪细胞在脂肪生成过程中起源于血管周围细胞。脂肪细胞释放的血管生成细胞因子在血管增殖反应中起作用。13号染色体的重排或缺失也可能与血管瘤有关。然而，以前没有窦性血管瘤与脂肪瘤等良性肿瘤相关的病例。在此，我们描述了一例不寻常的窦性血管瘤病例，该病例与一名43岁男性右上臂的脂肪瘤同时出现。
