School of Public Health, Physiotherapy and Population Science, University College Dublin, Belfield, Dublin 4, Ireland.
Disabil Rehabil. 2012;34(14):1149-56. doi: 10.3109/09638288.2011.635748. Epub 2011 Dec 8.
(i) to establish feasibility of the Astrand-Rhyming submaximal protocol using the adaptive ergometer in healthy participants, (ii) to test feasibility of this protocol in stroke patients, (iii) to identify clinical characteristics of stroke patients which limit testing, (iv) to establish criterion validity of V·O(2 steady state) ergometry data against the gold standard open-circuit spirometry measure and, lastly, (v) to test-retest reliability of the data generated by the test protocol.
A descriptive, cross sectional study design was implemented. Ten healthy participants (5 men, mean age 32 ± 6.6 y) and 20 chronic stroke patients (14 men, mean age 61.0 ± 11.6 y; mean months since stroke, 65.6 ± 34.4 y) took part in this study. Independent t-tests, Mann Whitney U tests and chi-square test identified characteristics of those who failed to successfully complete the protocol. Interclass correlation coefficients (ICCs) tested criterion validity and test-retest reliability.
No adverse events occurred. All healthy participants (100%) complied with the test protocol and estimation of V·O(2max). 90% of stroke patients completed the test, with V·O(2max) estimated in 35% (7 / 20) stroke patients. Age and beta-blocker medication demonstrated statistical significance as barriers to the test protocol at p = 0.04 and p = 0.03, respectively. Criterion validity established by comparison with breath-by-breath gas analysis was excellent (ICC 0.93). Retest reliability of V·O(2max), steady-state V·O(2) and oxygen pulse had ICCs of 0.94, 0.96 and 0.97, respectively.
The Astrand-Rhyming test protocol and MOTOmed Viva2 adaptive ergometer were feasible in healthy participants. The protocol was not feasible for V·O(2max) estimation for the majority of stroke patients based on heart rate response. The adapted steady state VO2 measures used however were feasible and had strong relationship to actual VO2 consumption. Criterion validity and retest reliability of test data were excellent.
(i) 用自适应测功计在健康受试者中建立 Astrand-Rhyming 亚极量方案的可行性,(ii) 测试该方案在中风患者中的可行性,(iii) 确定限制测试的中风患者的临床特征,(iv) 建立 V·O(2 稳态)测功数据与金标准闭路肺量计测量值的标准效度,最后,(v) 测试-重测该测试方案生成的数据的可靠性。
采用描述性、横断面研究设计。10 名健康受试者(5 名男性,平均年龄 32 ± 6.6 岁)和 20 名慢性中风患者(14 名男性,平均年龄 61.0 ± 11.6 岁;中风后平均时间 65.6 ± 34.4 岁)参加了这项研究。独立 t 检验、Mann-Whitney U 检验和卡方检验确定了未能成功完成方案的参与者的特征。组内相关系数(ICC)测试标准效度和测试-重测可靠性。
未发生不良事件。所有健康受试者(100%)均遵守测试方案和 V·O(2max)的估算。90%的中风患者完成了测试,其中 35%(7/20)的中风患者估计了 V·O(2max)。年龄和β受体阻滞剂药物在 p=0.04 和 p=0.03 时分别显示出对测试方案的统计学意义。与逐口气体分析相比,通过比较建立的标准效度非常好(ICC 0.93)。V·O(2max)、稳态 V·O(2)和氧脉冲的重测可靠性的 ICC 分别为 0.94、0.96 和 0.97。
Astrand-Rhyming 测试方案和 MOTOmed Viva2 自适应测功计在健康参与者中是可行的。该方案不适用于大多数中风患者的 V·O(2max)估计,因为他们的心率反应。然而,所使用的适应性稳态 VO2 测量是可行的,并且与实际 VO2 消耗有很强的关系。测试数据的标准效度和重测可靠性非常好。