Physical Therapy Department, Universidade Federal do Rio Grande do Norte UFRN, Natal-RN, Brazil.
J Cardiopulm Rehabil Prev. 2012 Jul-Aug;32(4):219-25. doi: 10.1097/HCR.0b013e318259b6a5.
Maximal oxygen uptake ((V)O(2max)) obtained from incremental exercise testing is a useful indicator of limited exercise capacity. Several prediction equations have been developed to estimate (V)O(2max) in patients with chronic obstructive pulmonary disease (COPD), but agreement studies between estimated and measured (V)O(2max) are lacking. This study aims to assess agreement between the 6 estimated (V)O(2max) evaluated during maximal incremental exercise testing in male COPD patients.
Patients with stable COPD, in accordance with GOLD guidelines, were included in the study. Agreement between (V)O(2max) obtained during incremental exercise testing and (V)O(2max) obtained from 6 prediction equations were studied. To estimate (V)O(2max) from anthropometric prediction equations, lung function variables and submaximal exercise testing were used.
Of the 60 male patients in the study, 12 were GOLD stage II, 24 GOLD stage III, and 24 GOLD stage IV. Five prediction equations underestimated the value of (V)O(2max) in relation to measured (V)O(2max) : equations 1, 2, 3, 4, and 6, by 14%, 66%, 42.2%, 35%, and 23.3%, respectively. Conversely, prediction equation 5 overestimated measured (V)O(2max) by 76.9%. Agreement between all (V)O(2max) prediction equations and measured (V)O(2max) was poor. Discrepancy between (V)O(2max) prediction equations and measured (V)O(2max) varied from 20.857 to 0.736 L/min.
The use of lung function at rest and submaximal exercise testing is inaccurate for determining (V)O(2max) , which cannot be estimated by prediction equations in patients with stable COPD.
递增运动测试得出的最大摄氧量（(V)O(2max)）是衡量运动受限能力的有用指标。已经开发了几种预测方程来估算慢性阻塞性肺疾病（COPD）患者的(V)O(2max)，但缺乏对估计值和实测值之间的一致性研究。本研究旨在评估 6 种在男性 COPD 患者最大递增运动测试中评估的预测(V)O(2max)之间的一致性。
根据 GOLD 指南，纳入稳定期 COPD 患者。研究了递增运动测试中获得的(V)O(2max)与 6 种预测方程获得的(V)O(2max)之间的一致性。为了从人体测量预测方程估算(V)O(2max)，使用了肺功能变量和亚最大运动测试。
在 60 名男性患者中，12 名处于 GOLD Ⅱ期，24 名处于 GOLD Ⅲ期，24 名处于 GOLD Ⅳ期。有 5 个预测方程低估了与实测(V)O(2max)的(V)O(2max)值：方程 1、2、3、4 和 6，分别低估了 14%、66%、42.2%、35%和 23.3%。相反，预测方程 5 高估了实测(V)O(2max)值，高出 76.9%。所有(V)O(2max)预测方程与实测(V)O(2max)之间的一致性较差。预测方程与实测(V)O(2max)之间的差异范围从 20.857 到 0.736 L/min。
使用静息时的肺功能和亚最大运动测试来确定(V)O(2max)是不准确的，不能用稳定期 COPD 患者的预测方程来估计。
