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挑战多发性骨髓瘤和其他癌症相关骨骼疾病的现行方法:从双磷酸盐类药物到靶向治疗。

Challenging the current approaches to multiple myeloma- and other cancer-related bone diseases: from bisphosphonates to targeted therapy.

机构信息

Department of Hematology and Oncology, University Medical Center Freiburg, Freiburg, Germany.

出版信息

Leuk Lymphoma. 2012 Jun;53(6):1057-61. doi: 10.3109/10428194.2011.644548. Epub 2012 Jan 13.

DOI:10.3109/10428194.2011.644548
PMID:22149167
Abstract

An international myeloma meeting entitled "Challenging the current approaches to multiple myeloma- and other cancer-related bone diseases: from bisphosphonates to targeted therapy" was held in Freiburg, Germany in July 2011 to discuss novel insights into and approaches to myeloma bone disease and other bone-seeking tumors. This review briefly summarizes the most prominent data of the meeting and current literature on our understanding of bone disease, the role of imaging techniques, operative interventions and systemic bone-seeking treatment, all of which should further improve our future therapeutic choices.

摘要

一个题为“挑战多发性骨髓瘤和其他癌症相关骨骼疾病的现行方法——从双磷酸盐类药物到靶向治疗”的国际骨髓瘤会议于 2011 年 7 月在德国弗莱堡举行,旨在讨论骨髓瘤骨骼疾病和其他骨骼趋向性肿瘤的新见解和方法。这篇综述简要总结了会议上最突出的数据和当前关于我们对骨骼疾病、成像技术、手术干预和全身性骨骼趋向性治疗的理解的文献,所有这些都应该进一步改善我们未来的治疗选择。

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Challenging the current approaches to multiple myeloma- and other cancer-related bone diseases: from bisphosphonates to targeted therapy.挑战多发性骨髓瘤和其他癌症相关骨骼疾病的现行方法:从双磷酸盐类药物到靶向治疗。
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Can oncology recapitulate paleontology? Lessons from species extinctions.肿瘤学能重现古生物学吗?物种灭绝带来的启示。
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European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma.欧洲骨髓瘤网络关于新诊断多发性骨髓瘤患者评估和治疗的建议。
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Intratibial injection of human multiple myeloma cells in NOD/SCID IL-2Rγ(null) mice mimics human myeloma and serves as a valuable tool for the development of anticancer strategies.NOD/SCID IL-2Rγ(null) 小鼠的胫骨内注射人多发性骨髓瘤细胞可模拟人类骨髓瘤,并成为开发抗癌策略的有价值工具。
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Disrupting the networks of cancer.扰乱癌症网络。
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