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[无色素性黑素瘤。18例病例研究]

[Amelanotic melanoma. Study of 18 cases].

作者信息

Rutowitsch M S, Garrido Neves R, Ferreira De Castro O

机构信息

Medicina pela Universidade Federal Fluminense, Doutorando em Dermatologia, Universidade Federal do Rio de Janeiro.

出版信息

Med Cutan Ibero Lat Am. 1990;18(1):49-57.

PMID:2214928
Abstract

The authors analyze a retrospective study of 18 cases of amelanotic melanoma, coming from 7 Departments of Dermatopathology, and 3 from private clinics in Brazil, during the period from 1980 through 1987. Nine of the 18 patients were men, and seven were women; 14 of the 18 were caucasian and 2 were blacks. Their average combined age was 56 years, varying from 24 years to 86 years. The average size of the lesions was 2.7 cm. and the location was: extremities = 7, thoracic wall = 5, upper limb = 2, and lower limb = 2. Only 2 cases included in this analyses, didn't have any other additional information about color, age, sex and location. The authors found that amelanotic melanoma is rare, in accordance with the literature. They point out, that the rarity or the lack of the melanic pigment within the tumors cells, makes the clinical diagnosis much more complex.

摘要

作者分析了一项回顾性研究,该研究涉及1980年至1987年期间来自巴西7个皮肤病理学部门以及3家私人诊所的18例无色素性黑色素瘤病例。18例患者中9例为男性,7例为女性;18例中有14例为白种人,2例为黑人。他们的平均年龄为56岁,年龄范围从24岁至86岁。病变的平均大小为2.7厘米,病变部位分布如下:四肢7例、胸壁5例、上肢2例、下肢2例。该分析中仅2例未包含有关颜色、年龄、性别和部位的任何其他附加信息。作者发现,根据文献记载,无色素性黑色素瘤很罕见。他们指出,肿瘤细胞内黑色素的罕见性或缺乏使得临床诊断更加复杂。

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