Halldorsson Jonas G, Flekkoy Kjell M, Arnkelsson Gudmundur B, Tomasson Kristinn, Magnadottir Hulda Bra, Arnarson Eirikur Orn
Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Brain Inj. 2012;26(1):1-13. doi: 10.3109/02699052.2011.635359.
To examine the scope of paediatric traumatic brain injury (TBI) as a health concern and to identify prognostic factors for TBI-related sequelae.
The study was prospective and nationwide. A questionnaire was sent to a study group (SG) of all 0-19 years old in Iceland, diagnosed ∼16 years earlier with TBI during a 1-year period, 1992-1993 (n = 550) and to a control group (CG) (n = 1232), selected from the National Register.
In the CG 49.5% reported having sustained TBI and 7.0% reported long-term disability. In the group with TBI, force of impact to the head, more than one incident of TBI and the injury severity by gender interaction predicted late symptoms. TBI severity had substantially less effect than force of impact and was close to non-existent for females.
Based on two independent nationwide samples, the scope of TBI as a health concern in adolescence and young adulthood is greater than previously documented. The findings suggest that TBI event-related factors, especially force of impact, have greater predictive value than clinical symptoms of severity at the acute stage, females being more sensitive to the effects of mild TBI than males.
研究小儿创伤性脑损伤（TBI）作为一个健康问题的范围，并确定TBI相关后遗症的预后因素。
该研究为前瞻性全国性研究。向冰岛所有0至19岁的研究组（SG）发放问卷，这些人在1992 - 1993年的1年期间约16年前被诊断为TBI（n = 550），并向从国家登记处选取的对照组（CG）（n = 1232）发放问卷。
在对照组中，49.5%的人报告曾遭受TBI，7.0%的人报告有长期残疾。在TBI组中，头部撞击力、不止一次的TBI事件以及性别交互作用下的损伤严重程度可预测后期症状。TBI严重程度的影响远小于撞击力，对女性而言几乎不存在影响。
基于两个独立的全国性样本，TBI作为青少年和青年期健康问题的范围比之前记录的更大。研究结果表明，与TBI事件相关的因素，尤其是撞击力，比急性期严重程度的临床症状具有更大的预测价值，女性对轻度TBI的影响比男性更敏感。
