Fernández-Redondo V, Losada A, Zulaica A, Cebreiro C, Cervantes R, Toribio J
Cátedra de Dermatología, Hospital General de Galicia, Facultad de Medicina, Santiago de Compostela, España.
Med Cutan Ibero Lat Am. 1990;18(2):96-100.
We report two cases of Dowling-Degos' disease, one affecting the vulvovaginal semimucose, and one associated to a terminal malignant neoplasia. We remark the importance of this knowledge in order to distinguish it from malignant acanthosis nigricans or other patterns of melanosis or lentiginosis when located within mucose or semimucose, specially at the genitals. All cases associated to malignant neoplasia described are emphasized. However Dowling-Degos' disease is considered to be a nonparaneoplasic genodermatoses, this association should be taken into account.
我们报告了两例Dowling-Degos病，一例累及外阴阴道半黏膜，另一例与终末期恶性肿瘤相关。我们强调了这一知识的重要性，以便在其位于黏膜或半黏膜部位，特别是生殖器部位时，将其与恶性黑棘皮病或其他黑素沉着或雀斑样痣模式相区分。文中着重描述了所有与恶性肿瘤相关的病例。然而，尽管Dowling-Degos病被认为是一种非副肿瘤性遗传性皮肤病，但这种关联仍应予以考虑。
