飞秒 LASIK 术后超高分辨率 OCT 下上皮基底膜破裂后角膜混浊。

Corneal haze following disruption of epithelial basement membrane on ultra-high-resolution OCT following femtosecond LASIK.

机构信息

Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.

出版信息

J Refract Surg. 2012 Jan;28(1):72-4. doi: 10.3928/1081597X-20111202-01. Epub 2011 Dec 9.

DOI:10.3928/1081597X-20111202-01

PMID:22149771

Abstract

PURPOSE

To analyze in vivo structural properties of a case with interface haze that developed after femtosecond laser-assisted LASIK.

METHODS

Case report.

RESULTS

A 42-year-old man underwent uncomplicated LASIK. Four months after the surgery he developed regression of his refractive error and interface haze in both eyes. Flap thickness was calculated as 73 μm and 81 μm in the right and left eyes, respectively. A novel ultra-high-resolution spectral domain optical coherence tomography (OCT) system was used to demonstrate in vivo morphology of the cornea. On ultra-high-resolution OCT, haze was demonstrated as increased bright white reflectivity of the flap interface. Areas of focal disruption of the basement membrane and Bowman layer corresponded with the most significant areas of interface haze.

CONCLUSIONS

Our results support the hypothesis that haze after femtosecond LASIK may be a result of damage to the basement membrane and Bowman layer of the cornea.

摘要

目的

分析飞秒激光辅助 LASIK 术后发生界面雾状混浊的病例的体内结构特征。

方法

病例报告。

结果

一名 42 岁男性接受了常规 LASIK 手术。术后 4 个月，他双眼的屈光不正和界面雾状混浊均出现回退。右眼和左眼的瓣厚度分别计算为 73μm 和 81μm。新型超高分辨率谱域光学相干断层扫描（OCT）系统用于显示角膜的体内形态。超高分辨率 OCT 显示，瓣界面的灰白色反射增加表明出现了雾状混浊。基底膜和 Bowman 层的局灶性破坏区域与界面雾状混浊最明显的区域相对应。