Kairemo K J, Hopsu E V
Division of Nuclear Medicine, Helsinki University Central Hospital.
Laryngoscope. 1990 Oct;100(10 Pt 1):1077-82.
Localization of primary tumors, metastases, or recurrences in 13 consecutive patients with histological verification of squamous cell or adenocarcinoma was made with radioimmunodetection using monoclonal radiolabeled anti-CEA antibody. All surgical specimens stained immunohistochemically, except one, were positive for CEA. Of the known 19 tumor sites 17 were visualized in antibody scans. There were two positive findings that did not prove to be positive during 12 month follow-up. The scintigram findings did not correlate with CEA serum concentrations that, with one exception, were normal in all patients.
使用单克隆放射性标记抗癌胚抗原（CEA）抗体通过放射免疫检测法对13例经组织学证实为鳞状细胞癌或腺癌的连续患者的原发性肿瘤、转移灶或复发灶进行定位。除1例手术标本外，所有经免疫组织化学染色的手术标本CEA均呈阳性。在已知的19个肿瘤部位中，17个在抗体扫描中显影。有2个阳性发现经12个月随访未证实为阳性。闪烁扫描结果与CEA血清浓度无关，所有患者中除1例血清浓度异常外，其余均正常。
