Hurmeric Volkan, Yoo Sonia H, Galor Anat, Canto Ana Paula, Wang Jianhua
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA.
Ophthalmic Surg Lasers Imaging. 2011 Dec 8;42 Online:e122-5. doi: 10.3928/15428877-20111201-05.
A 59-year-old woman presented with bilateral, peripheral, circular corneal infiltrates. There was a clear zone separating the outer margin of the degeneration from the limbus in both eyes. The inner margins were indistinct. Ultra-high-resolution optical coherence tomography (UHR-OCT) imaging demonstrated subepithelial infiltrations with epithelial thinning and corneal surface elevation. The infiltrate was accompanied by significant stromal scarring, which reached deep layers of the corneal stroma. UHR-OCT findings were consistent with Salzmann nodular degeneration. UHR-OCT can be used as an optical biopsy to diagnose atypical corneal degenerations without tissue sampling.
一名59岁女性出现双侧周边角膜圆形浸润。双眼均有一个清晰区域将变性的外缘与角膜缘分隔开。内缘不清晰。超高分辨率光学相干断层扫描（UHR-OCT）成像显示上皮下浸润伴上皮变薄和角膜表面隆起。浸润伴有显著的基质瘢痕形成，瘢痕延伸至角膜基质深层。UHR-OCT检查结果与萨尔茨曼结节状变性一致。UHR-OCT可作为一种光学活检手段，用于在不进行组织采样的情况下诊断非典型角膜变性。
