Department for Interventions in Health-Care Facilities, Hellenic Center for Disease Control and Prevention, 3-5 Agrafon Street, Athens, 15123 Greece.
BMC Med. 2011 Dec 8;9:131. doi: 10.1186/1741-7015-9-131.
Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease.
克里米亚-刚果出血热（CCHF）病毒是所有蜱传病毒中地理分布最广的病毒，在欧亚大陆和非洲的 30 多个国家流行。在过去的十年中，巴尔干半岛和邻近地区出现了新的或重新出现的焦点。在这里，我们讨论了影响 CCHF 发病率的因素，并重点讨论了使用利巴韦林治疗这种感染的主要问题。鉴于过去十年中 CCHF 的出现动态，迫切需要开发新的抗病毒药物和疫苗来治疗和预防这种急性、危及生命的疾病。
