Pereira M M, Andrade J
Instituto Oswaldo Cruz, Departamento de Bacteriologia, Rio de Janeiro, RJ, Brasil.
Mem Inst Oswaldo Cruz. 1990 Jan-Mar;85(1):47-52. doi: 10.1590/s0074-02761990000100007.
A serologic survey was carried out on slum dwellers in the city of Rio de Janeiro. A total of 259 serum samples from male and female individuals of different age groups were tested for the presence of antileptospire antibodies by microagglutination. Prevalence data were analyzed in relation to the major risk factors present at the site, mainly represented by the presence of carrier animals and the occurrence of frequent floods. Of the samples tested, 25% reacted with antigens of different serogroups at titres ranging from 1:100 to 1:6400, with a predominance of titres less than or equal to 1:400; 35% of positive sera reacted with leptospirae of the Icterohaemorrhagiae serogroup. Reactions with Djasiman, Panama, Javanica, Canicola, Pyrogenes, Australis, Ballum, Sejroe, Bataviae, Grippotyphosa, Autumnalis and Cynopteri were also detected, though at lower frequencies. There was no statistically significant difference between sexes, but higher prevalence rates were found to be associated with increasing age. A focus of infection was characterized, in which social and economic factors contribute to the persistence of leptospirae by favoring the proliferation of the main reservoir.
在里约热内卢市对贫民窟居民进行了一项血清学调查。通过微凝集试验，对来自不同年龄组的259名男性和女性个体的血清样本进行了抗钩端螺旋体抗体检测。分析了患病率数据与该地点存在的主要风险因素的关系，主要风险因素以携带动物的存在和频繁洪水的发生为代表。在检测的样本中，25%与不同血清群的抗原发生反应，滴度范围为1:100至1:6400，其中滴度小于或等于1:400的占多数；35%的阳性血清与出血性黄疸型血清群的钩端螺旋体发生反应。还检测到与爪哇、巴拿马、爪哇尼卡、犬型、热解型、澳洲型、拜伦型、赛罗型、巴达维亚型、波摩那型、秋季型和犬蝠型的反应，不过频率较低。性别之间没有统计学上的显著差异，但发现患病率随着年龄的增长而升高。确定了一个感染源，其中社会和经济因素通过促进主要宿主的繁殖而导致钩端螺旋体持续存在。
