与血流相关及 Willis 环动脉瘤相关的脑动静脉畸形。

Cerebral arteriovenous malformations associated with flow-related and circle of Willis aneurysms.

机构信息

Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

World Neurosurg. 2011 Nov;76(5):455-8. doi: 10.1016/j.wneu.2011.04.015.

DOI:10.1016/j.wneu.2011.04.015

PMID:22152575

Abstract

BACKGROUND

To evaluate the characteristics of brain arteriovenous malformations (AVMs) with coexisting flow-related and Willis circle aneurysms.

METHODS

The 302 consecutive retrospectively reviewed patients from the Beijing Tiantan Hospital were analyzed in this study. The presence of cerebral aneurysms was confirmed by pretreatment selective and superselective angiography. Univariate and multivariate analyses were performed for patient age, sex, history of rupture, associated aneurysms, AVM size, and deep and superficial venous drainage.

RESULTS

Of the 302 patients, 41 (13.6%) had AVMs associated with intranidal aneurysms, and 33 (10.9%) had AVMs associated with extranidal aneurysms. Of the 33 patients, 24 (72.7%) had a flow-related and 9 (27.3%) had a Willis circle aneurysm. Flow-related and Willis circle aneurysms correlated positively with intracranial hemorrhage (P = 0.003), patient age (P = 0.003), and infratentorial AVMs (P = 0.040) in multiple univariate analysis.

CONCLUSIONS

Flow-related and Willis circle aneurysms coexisting with cerebral AVMs frequently are associated with initial hemorrhage presentation, patient age, and infratentorial AVM location.

摘要

背景

评估同时存在血流相关性和 Willis 环动脉瘤的脑动静脉畸形（AVM）的特征。

方法

本研究分析了来自北京天坛医院的 302 例连续回顾性患者。通过预处理的选择性和超选择性血管造影术确认存在颅内动脉瘤。对患者年龄、性别、破裂史、相关动脉瘤、AVM 大小以及深静脉和浅静脉引流进行单变量和多变量分析。

结果

302 例患者中，41 例（13.6%）存在伴有瘤内动脉瘤的 AVM，33 例（10.9%）存在伴有瘤外动脉瘤的 AVM。在这 33 例患者中，24 例（72.7%）存在血流相关性动脉瘤，9 例（27.3%）存在 Willis 环动脉瘤。血流相关性和 Willis 环动脉瘤与颅内出血（P=0.003）、患者年龄（P=0.003）和幕下 AVM（P=0.040）在多项单变量分析中呈正相关。