Suppr超能文献

[变形杆菌对肠上皮的黏附]

[Proteus adhesion to intestinal epithelium].

作者信息

Parkhomenko L V, Gorbenko I M, Timokhina L V

出版信息

Mikrobiol Zh (1978). 1990 May-Jun;52(3):80-4.

PMID:2215291
Abstract

The adhesive properties of Proteus strains isolated from different sources have been studied under conditions similar to the real interaction of microorganisms with the epithelial cells of intestine. A comparison of the adhesive properties of Proteus and of colon Bacillus has shown that the value of the strong adhesion to the mucosa of Proteus isolated under enterocolitis at the same bulk concentrations of the infectious suspension is 2-3 order less than that of E. coli. The adhesion of Proteus to the surface of epithelial cells begins at bulk concentrations exceeding those for the colon Bacillus by 3-4 orders. Besides, a toxic effect of number of freshly isolated Proteus strains on the epithelial cells of intestine mucosa is observed. Strains isolated from patients with diarrhea and from environment differed from each other in the studied criteria. A conclusion is drawn that at the initial stage of the interaction with the intestine mucosa the Proteus strains differ considerably from the indigenous strain of the colon Bacillus in the ability to colonize the epithelial surface.

摘要

已在类似于微生物与肠上皮细胞实际相互作用的条件下,研究了从不同来源分离出的变形杆菌菌株的黏附特性。对变形杆菌和结肠杆菌黏附特性的比较表明,在相同感染悬液体积浓度下,在小肠结肠炎时分离出的变形杆菌对黏膜的强黏附值比大肠杆菌低2 - 3个数量级。变形杆菌对上皮细胞表面的黏附始于体积浓度超过结肠杆菌3 - 4个数量级时。此外,观察到一些新分离出的变形杆菌菌株对肠黏膜上皮细胞有毒性作用。从腹泻患者和环境中分离出的菌株在所研究的标准方面彼此不同。得出的结论是,在与肠黏膜相互作用的初始阶段,变形杆菌菌株在定殖于上皮表面的能力方面与结肠杆菌的本土菌株有很大差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验