Burak I I, Ozeretskovskaia N N
Med Parazitol (Mosk). 1990 May-Jun(3):38-41.
The experiments on mice experimentally infected with Trichinella larvae have established that in mild infection adhesive and killer cell reactions developed on day 14, reached their maximum on days 21-30 and began to attenuate on day 45. The cells from animals with moderate infection showed a higher immune activity which remained unchanged till day 90 of infection. The cells from mice with severe infection showed inhibition of immune activity which was most marked on days 21 and 30 of the infection. Eosinophiles and neutrophils are characterized by IgE-dependent cell adherence and killing activity, the involvement of macrophages in the responses seems to be insignificant.
对实验感染旋毛虫幼虫的小鼠进行的实验表明,在轻度感染时,黏附细胞和杀伤细胞反应在第14天出现,在第21 - 30天达到最大值,并在第45天开始减弱。中度感染动物的细胞表现出较高的免疫活性,在感染第90天前保持不变。重度感染小鼠的细胞表现出免疫活性受到抑制,在感染的第21天和第30天最为明显。嗜酸性粒细胞和中性粒细胞具有IgE依赖的细胞黏附及杀伤活性,巨噬细胞在这些反应中的参与似乎不显著。