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[小鼠实验性旋毛虫病中抗体依赖性细胞介导的免疫反应]

[Antibody-dependent cell-mediated immune reactions in experimental trichinelliasis in mice].

作者信息

Burak I I, Ozeretskovskaia N N

出版信息

Med Parazitol (Mosk). 1990 May-Jun(3):38-41.

PMID:2215372
Abstract

The experiments on mice experimentally infected with Trichinella larvae have established that in mild infection adhesive and killer cell reactions developed on day 14, reached their maximum on days 21-30 and began to attenuate on day 45. The cells from animals with moderate infection showed a higher immune activity which remained unchanged till day 90 of infection. The cells from mice with severe infection showed inhibition of immune activity which was most marked on days 21 and 30 of the infection. Eosinophiles and neutrophils are characterized by IgE-dependent cell adherence and killing activity, the involvement of macrophages in the responses seems to be insignificant.

摘要

对实验感染旋毛虫幼虫的小鼠进行的实验表明,在轻度感染时,黏附细胞和杀伤细胞反应在第14天出现,在第21 - 30天达到最大值,并在第45天开始减弱。中度感染动物的细胞表现出较高的免疫活性,在感染第90天前保持不变。重度感染小鼠的细胞表现出免疫活性受到抑制,在感染的第21天和第30天最为明显。嗜酸性粒细胞和中性粒细胞具有IgE依赖的细胞黏附及杀伤活性,巨噬细胞在这些反应中的参与似乎不显著。

相似文献

1
[Antibody-dependent cell-mediated immune reactions in experimental trichinelliasis in mice].[小鼠实验性旋毛虫病中抗体依赖性细胞介导的免疫反应]
Med Parazitol (Mosk). 1990 May-Jun(3):38-41.
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Trichinella spiralis infection in mice. Mechanism of the resistance in animals genetically selected for high and low antibody production.小鼠旋毛虫感染。高抗体产生和低抗体产生基因选择动物的抗性机制。
Immunology. 1978 Sep;35(3):519-22.
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Leucocytes and Trichinella spiralis. 3. Importance of heat labile and heat stable substances in peritoneal exudate fluid for cell adherence reactions to infective larvae.白细胞与旋毛虫。3. 腹膜渗出液中热不稳定和热稳定物质在对感染性幼虫的细胞黏附反应中的重要性。
Immunology. 1973 Nov;25(5):827-34.
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Antibody response to stage-specific Trichinella spiralis surface antigens in strong and weak responder mouse strains.
J Immunol. 1982 Aug;129(2):839-43.
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Antibody-mediated in-vivo cytotoxicity to Trichinella spiralis newborn larvae in immune rats.抗体介导的免疫大鼠对旋毛虫新生幼虫的体内细胞毒性作用。
Parasite Immunol. 1988 May;10(3):293-308. doi: 10.1111/j.1365-3024.1988.tb00222.x.
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[The effect of toluene and ammonia on the invasive process and immunological indices in experimental trichinelliasis in mice].[甲苯和氨对小鼠实验性旋毛虫病侵袭过程及免疫指标的影响]
Med Parazitol (Mosk). 1991 Sep-Oct(5):47-9.
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[Cross immunity to superinfection between Trichinella spiralis and T. pseudospiralis in white mice and rats].[旋毛虫与伪旋毛虫在小白鼠和大鼠中对重复感染的交叉免疫]
Parazitologiia. 1974 Jul-Aug;8(4):299-301.
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[Preliminary study on congenital transmission of Trichinella spiralis in mice].旋毛虫在小鼠体内先天性传播的初步研究
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2005 Apr 30;23(2):73-7.
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Immunization of laboratory animals with ultraviolet-attenuated larvae against homologous challenge infection with Trichinella britovi.用紫外线减毒幼虫对实验动物进行免疫,以抵抗同源的布氏旋毛虫攻击感染。
Southeast Asian J Trop Med Public Health. 1998 Sep;29(3):563-6.
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Comparative studies on cell-mediated immunity in experimental trichinnellosis. Macrophage migration inhibition and cell adherence around larva in vitro.实验性旋毛虫病中细胞介导免疫的比较研究。体外巨噬细胞游走抑制及幼虫周围细胞黏附
Wiad Parazytol. 1975;21(4-5):639-48.

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