Department of Spine Surgery, Neurosciences Center, King Fahad Medical City, Riyadh, Saudi Arabia.
World Neurosurg. 2012 Jan;77(1):146-52. doi: 10.1016/j.wneu.2011.04.021. Epub 2011 Nov 17.
The aim of this study is to describe six cases with spontaneous resorption of sequestrated intervertebral disc herniation observed using magnetic resonance imaging. In addition, the possible mechanisms, predictive factors of spontaneous disappearance of the sequestrated disc herniation, and the proper surgical timing were discussed and reviewed in literature.
All the studied cases experienced acute radicular pain due to sequestrated intervertebral disc herniation; they refused surgery and were treated conservatively, and they were followed up neurologically and radiologically in the outpatient clinic in regular visits.
The studied cases included five cases with lumbar disc herniation (three at level L4-5 and two at level L5-S1) and one case with cervical disc herniation at level C5-6. All patients recovered from their radicular pain within 3 to 6 weeks, and it was correlated with resorption of their sequestrated intervertebral disc herniation as documented in their follow-up magnetic resonance imaging at 4 to 9 months.
We found that sequestrated disc herniation has potential for regression, which can be clearly demonstrated by magnetic resonance imaging, because of having higher water content, and therefore, may regress through both dehydration and inflammation-mediated resorption. We suggest conservative treatment in the initial course of the sequestrated type of disc herniation for at least 2 months before recommending surgical intervention unless severe neurologic deterioration takes place.
本研究旨在描述 6 例使用磁共振成像观察到的游离型椎间盘突出自发性吸收的病例。此外,还讨论并回顾了文献中游离型椎间盘突出自发性消失的可能机制、预测因素和适当的手术时机。
所有研究病例均因游离型椎间盘突出症急性神经根痛就诊;他们拒绝手术,接受保守治疗,并在门诊定期进行神经和影像学随访。
研究病例包括 5 例腰椎间盘突出症(3 例位于 L4-5 水平,2 例位于 L5-S1 水平)和 1 例 C5-6 颈椎间盘突出症。所有患者的神经根痛均在 3 至 6 周内缓解,与随访磁共振成像显示的游离型椎间盘突出吸收相关,随访时间为 4 至 9 个月。
我们发现游离型椎间盘突出症具有潜在的退行性变,这可以通过磁共振成像清楚地显示出来,因为游离型椎间盘突出症具有更高的含水量,因此可能通过脱水和炎症介导的吸收而消退。我们建议对游离型椎间盘突出症在初始阶段至少进行 2 个月的保守治疗,然后再建议手术干预,除非出现严重的神经功能恶化。