Pellegrini L, Mercier M-F, Cornese A, Blasco V, Albanèse J
Service d'anesthésie réanimation, hôpital de Timone, CHU Timone, AP-HM, 264, rue Saint-Pierre, 13385 Marseille, France.
Ann Fr Anesth Reanim. 2012 Feb;31(2):155-7. doi: 10.1016/j.annfar.2011.10.031. Epub 2011 Dec 6.
We report in this clinical case the successful use of a combination of rocuronium and sugammadex in a patient with Steinert myotonic dystrophy to perform a rapid sequence induction of anaesthesia. The patient had both contraindication to succinylcholine and a risk of prolonged neuromuscular blockade with non-depolarizing neuromuscular blocking agents. The use of high dose rocuronium (1mg/kg) allowed a quick and easy orotracheal intubation but induced a prolonged neuromuscular block, reversed with success by sugammadex (8 mg/kg).
我们在此临床病例中报告，在一名患有斯坦纳特肌强直性营养不良的患者中成功联合使用罗库溴铵和舒更葡糖钠进行快速顺序诱导麻醉。该患者既对琥珀酰胆碱有禁忌证，又有使用非去极化神经肌肉阻滞剂导致神经肌肉阻滞延长的风险。使用高剂量罗库溴铵（1mg/kg）可实现快速且容易的经口气管插管，但会导致神经肌肉阻滞延长，而舒更葡糖钠（8mg/kg）成功逆转了这种阻滞。
