Cyclotron Research Centre, University of Liège, Liege, Belgium.
J Affect Disord. 2012 Feb;136(3):398-404. doi: 10.1016/j.jad.2011.11.013. Epub 2011 Dec 10.
To date, most researchers rely on suicidal items of scales primarily designed to measure depression severity to capture suicidal ideation (SI). This study aims at investigating how well the suicide item of the clinician rated Hamilton Scale for Depression (HAM-D) and principal factors derived from this scale correlate with SI scores derived from a well validated measure of SI: the Beck's scale for SI (SSI).
281 suicide attempters consecutively hospitalized between 2007 and 2009 were assessed by using the SSI, the HAM-D and the self-report Beck Depression Inventory (BDI). Principal Component Analysis (PCA) was computed to extract main factors. Correlations between these factors, BDI's and HAM-D's suicide items and the SSI scores were then computed.
Three components were derived from the PCA. Factor 2 showed a major loading for the HAM-D suicide item. Both the HAM-D suicide item and Factor 2 positively correlated with the SSI total score (both p<0.00001). Moreover, the BDI suicide item highly correlated with the Factor 2 (p<0.001) and the SSI total score (p<0.00001). Finally, the HAM-D suicide item correlated significantly with the number of suicide attempts (p=0.0001) and the age at the first attempt (p=0.002).
Our sample was heterogeneous and future studies should refine the taxonomy of the suicidal behavior in specific sub-populations. The study design was cross-sectional and replication in a prospective study is needed.
These findings suggest that the use of a single suicide item or a dimensional factor derived from a depression scale might be a valid approach to assess the suicidal ideations. Moreover, the results suggest that clinician rated scales as well as self-report questionnaires are equally valid to do so.
迄今为止,大多数研究人员主要依靠专为衡量抑郁严重程度而设计的量表中的自杀项目来捕捉自杀意念(SI)。本研究旨在探讨临床医生评定的汉密尔顿抑郁量表(HAM-D)中的自杀项目以及从该量表中得出的主要因素与从经过充分验证的 SI 测量工具:贝克自杀意念量表(SSI)中得出的 SI 评分的相关性。
2007 年至 2009 年连续住院的 281 名自杀未遂者使用 SSI、HAM-D 和自我报告贝克抑郁量表(BDI)进行评估。计算主成分分析(PCA)以提取主要因素。然后计算这些因素、BDI 和 HAM-D 的自杀项目与 SSI 评分之间的相关性。
从 PCA 中得出了三个因素。因素 2 对 HAM-D 的自杀项目有较大的负荷。HAM-D 的自杀项目和因素 2 均与 SSI 总分呈正相关(均 p<0.00001)。此外,BDI 的自杀项目与因素 2(p<0.001)和 SSI 总分(p<0.00001)高度相关。最后,HAM-D 的自杀项目与自杀企图次数(p=0.0001)和首次尝试的年龄(p=0.002)显著相关。
我们的样本具有异质性,未来的研究应该在特定亚人群中细化自杀行为的分类。研究设计为横断面研究,需要前瞻性研究进行复制。
这些发现表明,使用单一自杀项目或从抑郁量表中得出的维度因素可能是评估自杀意念的有效方法。此外,结果表明,临床医生评定的量表和自我报告的问卷同样有效。