Loomba Rohit S, Arora Rohit R, Chandrasekar Suraj, Shah Parinda H
Department of Pediatrics, Children's Hospital of Wisconsin, Medical College of Wisconsin Affiliated Hospitals, Wauwatosa, Wisconsin, USA.
Blood Coagul Fibrinolysis. 2012 Mar;23(2):168-71. doi: 10.1097/MBC.0b013e32834cb25b.
Deep vein thrombosis may be a complication of extended length hospital stays. Immobilized patients, such as patients in the postoperative period, are at particularly high risk of developing a deep vein thrombosis, which can be associated with high levels of morbidity and mortality. Due to this, prevention of deep vein thrombosis is of great importance in the inpatient setting. Compression stockings have proven to play an important role in prophylaxis and may be used in their knee-length or thigh-length variety. Although randomized trials have studied the efficacy of both varieties in prevention of deep vein thrombosis, selection is often made without regard to evidence. This meta-analysis pools the findings of current studies comparing knee-length and thigh-length compression stockings for deep vein thrombosis prophylaxis. A fixed effects model was used for this study with a two-sided α-error less than 0.05 considered to be statistically significant. When both varieties of compression stockings are compared, thigh-length stockings offer a risk reduction in deep vein thrombosis development when compared with knee-length (odds ratio 1.197, confidence interval 0.983-1.458). This, however, is an insignificant finding. This analysis concludes that current data does not favor either thigh-length or knee-length compression stockings when it comes to prophylaxis of deep vein thrombosis.
深静脉血栓形成可能是长期住院的并发症。行动不便的患者，如术后患者，发生深静脉血栓形成的风险特别高，这可能与高发病率和死亡率相关。因此，在住院环境中预防深静脉血栓形成非常重要。弹力袜已被证明在预防中发挥重要作用，可使用膝长或大腿长款式。尽管随机试验研究了这两种款式在预防深静脉血栓形成方面的疗效，但选择时往往不考虑证据。这项荟萃分析汇总了当前比较膝长和大腿长弹力袜预防深静脉血栓形成的研究结果。本研究使用固定效应模型，双侧α错误小于0.05被认为具有统计学意义。当比较这两种弹力袜时，与膝长弹力袜相比，大腿长弹力袜在深静脉血栓形成的发生风险降低方面有优势（优势比1.197，置信区间0.983 - 1.458）。然而，这一发现并不显著。该分析得出结论，就预防深静脉血栓形成而言，目前的数据并不支持大腿长或膝长弹力袜中的任何一种。
