Istanbul University, Faculty of Dentistry, Department of Oral Implantology, Istanbul, Turkey.
Med Oral Patol Oral Cir Bucal. 2012 Jan 1;17(1):e69-75. doi: 10.4317/medoral.17263.
The aims of this study were to investigate the incidence of bacteremia, bacteriology and antibiotic susceptibility against to causative bacteria associated with dental implant installation.
30 generally healthy patients were enrolled in this study. Blood samples were collected at baseline and at 30 minutes after dental implant installation and 24 hours after dental implant surgery. Blood samples were cultured in a BACTEC system. The isolated bacteria were identified using conventional methods. Antimicrobial sensitivity tests were performed by disc diffusion.
No bacteria were isolated at the baseline and 24 hours after surgery, whereas the prevalence of bacteremia at 30 minutes after dental implant installation was 23%. The isolated bacteria species were Staphylococcus epidermidis, Eubacterium spp., Corynebacterium spp. and Streptococcus viridans. The Staphylococcus epidermidis, which was isolated in three patients, was found to be resistant to penicillin which is first choice of many clinicians.
Our findings suggest that installation of dental implants can produce bacteremia. Within the limitations of this study, it can be speculated that the resistance of antibiotics may compromise the routine prophylaxis against infective endocarditis. Therefore use of blood cultures and antibiograms may be suggested in risky patients. The outcome of the present study should be verified using a larger patient group with varying conditions.
本研究旨在调查与牙种植体植入相关的细菌引起的菌血症的发生率、细菌学和对抗生素的敏感性。
本研究纳入了 30 名一般健康的患者。在基线时、牙种植体植入后 30 分钟和牙种植手术后 24 小时采集血样。血样在 BACTEC 系统中培养。使用常规方法鉴定分离出的细菌。通过药敏纸片扩散法进行抗菌敏感性试验。
基线和手术后 24 小时均未分离出细菌，而牙种植体植入后 30 分钟菌血症的患病率为 23%。分离出的细菌种类为表皮葡萄球菌、真杆菌属、棒状杆菌属和草绿色链球菌。在 3 名患者中分离出的表皮葡萄球菌对许多临床医生首选的青霉素具有耐药性。
我们的研究结果表明，牙种植体的植入会产生菌血症。在本研究的限制范围内，可以推测抗生素的耐药性可能会影响常规预防感染性心内膜炎。因此，建议在高危患者中使用血培养和药敏试验。本研究的结果应使用具有不同条件的更大患者群体进行验证。
