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What is the role for the inflammasome in burn injury and sepsis?

作者信息

Gentile Lori F, Moldawer Lyle L

出版信息

Shock. 2012 Jan;37(1):124-5. doi: 10.1097/SHK.0b013e31823b7643.

Abstract
摘要

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本文引用的文献

1
A protective role for inflammasome activation following injury.
Shock. 2012 Jan;37(1):47-55. doi: 10.1097/SHK.0b013e318234f7ff.
2
Inflammasomes: caspase-1-activating platforms with critical roles in host defense.
Front Microbiol. 2011 Jan 25;2:3. doi: 10.3389/fmicb.2011.00003. eCollection 2011.
3
Emerging inflammasome effector mechanisms.
Nat Rev Immunol. 2011 Mar;11(3):213-20. doi: 10.1038/nri2936.
4
Inhibition of caspase-1 activation in Gram-negative sepsis and experimental endotoxemia.
Crit Care. 2011;15(1):R27. doi: 10.1186/cc9974. Epub 2011 Jan 18.
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NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
Nat Rev Immunol. 2010 Mar;10(3):210-5. doi: 10.1038/nri2725. Epub 2010 Feb 19.
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Neuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats.
Surg Neurol. 2008 Jun;69(6):561-7. doi: 10.1016/j.surneu.2007.03.041. Epub 2008 Feb 8.
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Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18.
Am J Respir Crit Care Med. 2006 Nov 1;174(9):1003-10. doi: 10.1164/rccm.200604-546OC. Epub 2006 Aug 14.
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Severe injury triggers antigen-specific T-helper cell dysfunction.
Shock. 1999 Jul;12(1):39-45. doi: 10.1097/00024382-199907000-00006.

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