Machan Carolyn M, Hrynchak Patricia K, Irving Elizabeth L
School of Optometry, University of Waterloo, Waterloo, Ontario, Canada.
Optom Vis Sci. 2012 Feb;89(2):130-6. doi: 10.1097/OPX.0b013e31823ee062.
To report on the prevalence of age-related (AR) cataract in an optometric clinic population including male and female subgroups.
Retrospective patient file data reviewed for the Waterloo Eye Study database included age, sex, date of lens extraction (LE), and presence of AR cataract [nuclear sclerosis (NS), cortical cataracts (CC), posterior subcapsular (PSC) or associated LE]. Prevalence (%) was calculated for overall AR cataract, NS, CC, PSC, and bilateral LE for all Waterloo Eye Study patients. Logistic regression analysis was used to create age functions for overall AR prevalence and for significant differences in cataract types for males and females. The distribution of homogeneous and mixed cataract and mean age of first LE were determined for males and females.
The prevalence of all AR, NS, CC, PSC, and bilateral LE was 35.3, 28.8, 9.9, 3.6, and 14.0%, respectively. Being female was associated with an increased prevalence of CC (odds ratio = 1.54, 95% confidence interval, 1.27 to 1.88) and bilateral LE (odds ratio = 1.41, 95% confidence interval, 1.09 to 1.84). Females reached 50% prevalence earlier than men for CC (76.7 vs. 82.6 years, p 0.05) and bilateral LE (84.6 vs. 90.5 years, p 0.05). Males had an earlier age of first LE than females (70.4 vs. 73.2 years; p 0.01).
Logistic regression modeling indicates that being female in this optometric clinic population was associated with an increased prevalence of CC, mixed cataract, surgical intervention, and later age of first LE. These data are important for public health planning.
报告验光诊所人群中年龄相关性（AR）白内障的患病率，包括男性和女性亚组。
回顾滑铁卢眼研究数据库中的患者档案数据，包括年龄、性别、晶状体摘除日期（LE）以及AR白内障的存在情况[核硬化（NS）、皮质性白内障（CC）、后囊下（PSC）或相关的LE]。计算所有滑铁卢眼研究患者中总体AR白内障、NS、CC、PSC和双侧LE的患病率（%）。采用逻辑回归分析来创建总体AR患病率以及男性和女性白内障类型显著差异的年龄函数。确定男性和女性中同质和混合性白内障的分布以及首次LE的平均年龄。
所有AR、NS、CC、PSC和双侧LE的患病率分别为35.3%、28.8%、9.9%、3.6%和14.0%。女性与CC患病率增加相关（优势比 = 1.54，95%置信区间，1.27至1.88）以及双侧LE患病率增加相关（优势比 = 1.41，95%置信区间，1.09至1.84）。女性CC患病率达到50%的年龄早于男性（76.7岁对82.6岁，p < 0.05），双侧LE患病率达到50%的年龄也早于男性（84.6岁对90.5岁，p < 0.05）。男性首次LE的年龄早于女性（70.4岁对73.2岁；p < 0.01）。
逻辑回归模型表明，在该验光诊所人群中，女性与CC、混合性白内障、手术干预的患病率增加以及首次LE年龄较晚相关。这些数据对公共卫生规划很重要。
