新西兰黑鼠（NZB）淋巴组织中嗜异性小鼠白血病病毒基因组表达的变化
Variations in expression of xenotropic murine leukemia virus genomes in lymphoid tissues of NZB mice.
作者信息
Morse H C, Chused T M, Sharrow S O, Hartley J W
出版信息
J Immunol. 1979 Jun;122(6):2345-8.
PMID:221584
Abstract
Lymphocytes from Thy, Sp, LN, and BM and NZB mice were tested for expression of X-MuLV genomes as cell surface gp70 (XenCSA) or infectious virus. The results demonstrate major dissociations for these parameters of X-MuLV expression in different lymphoid compartments and suggest that factors involved in T lymphocyte differentiation modify the levels of expression in these two modes.
摘要
对来自甲状腺、脾脏、淋巴结和骨髓的淋巴细胞以及新西兰黑小鼠（NZB）的淋巴细胞进行检测，以确定X-MuLV基因组作为细胞表面糖蛋白70（XenCSA）或传染性病毒的表达情况。结果表明，在不同淋巴区室中，X-MuLV表达的这些参数存在主要差异，这表明参与T淋巴细胞分化的因素会改变这两种模式下的表达水平。
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