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先天性偏瘫患儿脑损伤的形态学。计算机断层扫描研究。

Morphology of cerebral lesions in children with congenital hemiplegia. A study with computed tomography.

作者信息

Wiklund L M, Uvebrant P, Flodmark O

机构信息

Department of Diagnostic Radiology, University of Gothenburg, Sweden.

出版信息

Neuroradiology. 1990;32(3):179-86. doi: 10.1007/BF00589107.

Abstract

This study has analysed the results of CT scans of the brains in children with congenital hemiplegia. The material consists of 111 out of a total of 151 children with this cerebral palsy syndrome in a population-based series. We have classified the morphological findings in five groups. The groups are designed to reflect the phase of maturation of the brain when the insult happened. The groups are: 1. Maldevelopment, 2. Periventricular atrophy, 3. Cortical-/subcortical atrophy, 4. Miscellaneous, 5. Normal. In contrast to previous reports we found a high proportion (17%) with maldevelopment. However the dominating morphological pattern was periventricular atrophy, consistent with a hypoxic-ischemic insult to the immature brain, seen in 42%. Cortical and/or subcortical atrophy was found in 12%. Three children (3%) presented with morphological patterns not possible to classify. The group with no pathology according to CT was 26%.

摘要

本研究分析了先天性偏瘫患儿脑部CT扫描的结果。该材料来自一项基于人群的系列研究,共151例患有这种脑瘫综合征的儿童,其中111例纳入研究。我们将形态学发现分为五组。这些组旨在反映脑损伤发生时大脑的成熟阶段。分组如下:1. 发育异常;2. 脑室周围萎缩;3. 皮质/皮质下萎缩;4. 其他;5. 正常。与之前的报告不同,我们发现发育异常的比例较高(17%)。然而,主要的形态学模式是脑室周围萎缩,这与未成熟脑的缺氧缺血性损伤一致,占42%。皮质和/或皮质下萎缩占12%。三名儿童(3%)呈现出无法分类的形态学模式。CT显示无病变的组占26%。

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