Alissa Ahmed, Al Eisa Abdulla, Huma Rozeena, Mulekar Sajeev
Dermatology National Center for Vitiligo and Psoriasis, Riyadh, Kingdom of Saudi Arabia.
Saudi Med J. 2011 Dec;32(12):1291-6.
To assess the clinical patterns, epidemiological profile of vitiligo, and its awareness among Saudi nationals.
A retrospective study was conducted among Saudi nationals with a confirmed diagnosis of vitiligo presenting to the National Center for Vitiligo and Psoriasis, Riyadh, Saudi Arabia, from August 2002 to August 2006 using a retrospective questionnaire based on the history and medical records of patients.
Of the 4134 cases, 53.5% were females. The mean age of onset of vitiligo was 17.4 years. Vitiligo vulgaris was the most common type in 42.3% of cases, 90.5% had no associated autoimmune conditions. The family history was positive in 42.8%. Twenty-nine percent developed depigmentation on multiple sites, and 68.2% over exposed areas. Nearly 1912 (46.2%) were not aware of its cause, and 2682 (64.9%) were unaware of aggravating factors. Stress as an aggravating factor was considered by 15.1%. Herbal treatments were considered very effective by 45.8%.
Vitiligo is affecting Saudi women more than men with an early age of onset. Vitiligo vulgaris being the most prevalent form with a high rate of positive family history and low rate of associated autoimmune diseases. Knowledge of genetic and environmental factors affecting vitiligo is poorly conveyed and explored.
评估白癜风的临床模式、流行病学特征以及沙特国民对其的认知情况。
采用回顾性问卷调查，基于患者的病史和病历，对2002年8月至2006年8月期间就诊于沙特阿拉伯利雅得白癜风与银屑病国家中心、确诊为白癜风的沙特国民进行回顾性研究。
在4134例病例中，53.5%为女性。白癜风的平均发病年龄为17.4岁。寻常型白癜风是最常见的类型，占42.3%的病例，90.5%无相关自身免疫性疾病。家族史阳性率为42.8%。29%的患者在多个部位出现色素脱失，68.2%在暴露部位出现色素脱失。近1912例（46.2%）不知道其病因，2682例（64.9%）不知道加重因素。15.1%的患者认为压力是加重因素。45.8%的患者认为草药治疗非常有效。
白癜风对沙特女性的影响大于男性，发病年龄较早。寻常型白癜风是最常见的类型，家族史阳性率高，相关自身免疫性疾病发生率低。关于影响白癜风的遗传和环境因素的知识传播和探索不足。
