Graus F, Abos J, Roquer J, Mazzara R, Pereira A
Department of Neurology, Hospital Clinic Provincial, Spain.
Neurology. 1990 Oct;40(10):1621-3. doi: 10.1212/wnl.40.10.1621.
We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.