Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel.
Chem Biodivers. 2011 Dec;8(12):2322-30. doi: 10.1002/cbdv.201000363.
Hordeum spontaneum, wild barley, is the direct progenitor of domestic barley, Hordeum vulgare, an economically important ingredient of animal feed, beer, soy sauce, and more recently, of nutraceuticals. Domestic barley has also been used in the past as a medicine. Barley is a rich source of tocotrienols, with α-tocotrienol being the most prevalent. Wild barley seeds were harvested from ecogeographically diverse areas across the Fertile Crescent, and the tocopherol (α-δ) and tocotrienol (α-δ) contents were determined. Diversity differences in individual and total 'tocol' values were significant between and within specific countries, and were significantly correlated with temperature. Wild barley may be used in the future to improve functional qualities of domestic barley. 'Tocolome' and 'tocolomics' are proposed to encompass all tocols and potentially synergy-enhancing 'entourage' compounds that may occur in tocols' 'metabolomic neighborhoods', aiding the standardized manufacture of complex barley derivatives for nutraceutical and pharmaceutical functions.
野生大麦是家麦的直系祖先，也是动物饲料、啤酒、酱油等的重要经济成分，最近更是成为了营养保健品的成分之一。过去，大麦也被用作药物。大麦是生育三烯酚的丰富来源，其中以α-生育三烯酚最为普遍。野生大麦种子是从新月沃地不同生态地理区域采集而来的，测定了它们的生育酚（α-δ）和生育三烯酚（α-δ）的含量。不同国家之间以及同一国家内的个体和总“tocol”值的多样性差异显著，且与温度显著相关。未来，野生大麦可能被用于改善家麦的功能特性。提议采用“tocolome”和“tocolomics”来涵盖所有生育酚以及可能存在于生育酚“代谢组学邻域”中的协同增强“伴生”化合物，这有助于标准化制造用于营养保健品和药物功能的复杂大麦衍生物。
