Pediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Int J Environ Res Public Health. 2011 Nov;8(11):4353-66. doi: 10.3390/ijerph8114353. Epub 2011 Nov 21.
Malnutrition affects 50% of hospitalized children and 25-70% of the critically ill children. It increases the incidence of complications and mortality. Malnutrition is associated with an altered metabolism of certain substrates, increased metabolism and catabolism depending on the severity of the lesion, and reduced nutrient delivery. The objective should be to administer individualized nutrition to the critically ill child and to be able to adjust the nutrition continuously according to the metabolic changes and evolving nutritional status. It would appear reasonable to start enteral nutrition within the first 24 to 48 hours after admission, when oral feeding is not possible. Parenteral nutrition should only be used when enteral nutrition is contraindicated or is not tolerated. Energy delivery must be individually adjusted to energy expenditure (40-65 kcal/100 calories metabolized/day) with a protein delivery of 2.5-3 g/kg/day. Frequent monitoring of nutritional and metabolic parameters should be performed.
营养不良影响 50%的住院儿童和 25-70%的重症儿童。它会增加并发症和死亡率。营养不良与某些底物代谢的改变、代谢和分解代谢的增加有关,具体取决于损伤的严重程度,以及营养素输送的减少。目标应该是为重症儿童提供个体化的营养,并能够根据代谢变化和不断变化的营养状况持续调整营养。在无法进行口服喂养的情况下,在入院后 24 至 48 小时内开始进行肠内营养似乎是合理的。只有在肠内营养禁忌或不耐受时才应使用肠外营养。能量输送必须根据能量消耗(40-65 kcal/100 卡代谢/天)进行个体化调整,蛋白质输送量为 2.5-3 g/kg/天。应经常监测营养和代谢参数。