Jiménez Jiménez F J, Cervera Montes M, Blesa Malpica A L
Hospital Universitario Virgen del Rocío, Sevilla, España.
Med Intensiva. 2011 Nov;35 Suppl 1:81-5. doi: 10.1016/S0210-5691(11)70017-1.
Patients with cardiac disease can develop two types of malnutrition: cardiac cachexia, which appears in chronic congestive heart failure, and malnutrition due to the complications of cardiac surgery or any other type of surgery in patients with heart disease. Early enteral nutrition should be attempted if the oral route cannot be used. When cardiac function is severely compromised, enteral nutrition is feasible, but supplementation with parenteral nutrition is sometimes required. Sustained hyperglycemia in the first 24 hours in patients admitted for acute coronary syndrome, whether diabetic or not, is a poor prognostic factor for 30-day mortality. In critically-ill cardiac patients with stable hemodynamic failure, nutritional support of 20-25 kcal/kg/day is effective in maintaining adequate nutritional status. Protein intake should be 1.2*-1.5 g/kg/day. Routine polymeric or high protein formulae should be used, according to the patient's prior nutritional status, with sodium and volume restriction according to the patient's clinical situation. The major energy source for myocytes is glutamine, through conversion to glutamate, which also protects the myocardial cell from ischemia in critical situations. Administration of 1 g/ day of omega-3 (EPA+DHA) in the form of fish oil can prevent sudden death in the treatment of acute coronary syndrome and can also help to reduce hospital admission for cardiovascular events in patients with chronic heart failure.
一种是出现在慢性充血性心力衰竭中的心脏恶病质,另一种是因心脏病患者进行心脏手术或任何其他类型手术的并发症导致的营养不良。如果无法采用口服途径,应尝试早期肠内营养。当心脏功能严重受损时,肠内营养是可行的,但有时需要补充肠外营养。急性冠状动脉综合征患者,无论是否患有糖尿病,入院后最初24小时内持续高血糖是30天死亡率的不良预后因素。对于血流动力学稳定的重症心脏病患者,每天20 - 25千卡/千克的营养支持可有效维持足够的营养状况。蛋白质摄入量应为每天1.2 - 1.5克/千克。应根据患者先前的营养状况使用常规的聚合物或高蛋白配方,并根据患者的临床情况限制钠和液体摄入量。心肌细胞的主要能量来源是谷氨酰胺,它通过转化为谷氨酸,在危急情况下还能保护心肌细胞免受缺血损伤。以鱼油形式每天给予1克ω-3(二十碳五烯酸+二十二碳六烯酸)可预防急性冠状动脉综合征治疗中的猝死,还可帮助减少慢性心力衰竭患者因心血管事件住院的次数。