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[人类机会性感染病原体——常见病原菌抗生素敏感性测定方法的比较分析]

[Comparative analysis of the antibiotic sensitivity determination methods of conventionally pathogenic bacteria--agents of human opportunistic infections].

作者信息

Kulia A F, Sabo Iu, Koval' H M, Boĭko N V

出版信息

Mikrobiol Z. 2011 Sep-Oct;73(5):47-53.

PMID:22164699
Abstract

Investigation of biological properties of pathogenic bacteria and, first of all, their sensitivity to antibiotics is the key to successful treatment of human opportunistic infections and to selection of appropriate tactics of their prevention. This paper is devoted to the comparative characteristic of modem and classical approaches to determination of sensitivities to antibiotics of conventionally pathogenic bacteria: methods applied in Ukraine and recommendations proposed by European Committee aimed to unify all the methods of testing sensitivity to antimicrobial agents (EUCAST). The major differences of the above-mentioned methods of testing sensitivity of clinical and non-clinical isolates of potentially pathogenic bacteria to antibiotics have been examined in order to confirm the feasibility of usage and permanent updating the EUCAST database and to promote creation of the appropriate unifield national electronic resource.

摘要

对病原菌生物学特性的研究,首先是它们对抗生素的敏感性,是成功治疗人类机会性感染以及选择合适预防策略的关键。本文致力于对现代和经典方法进行比较,以确定传统病原菌对抗生素的敏感性:乌克兰应用的方法以及欧洲委员会提出的旨在统一所有抗菌药物敏感性检测方法的建议(欧洲抗菌药物敏感性试验委员会)。研究了上述检测潜在病原菌临床和非临床分离株对抗生素敏感性方法的主要差异,以确认使用欧洲抗菌药物敏感性试验委员会数据库并不断更新的可行性,并促进创建合适的统一国家电子资源。

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