Plastic and Reconstructive Surgery Department, Inonu University School of Medicine, Malatya Turkey.
Eur Rev Med Pharmacol Sci. 2011 Oct;15(10):1207-11.
Reduction mammoplasty (RM) is one of the most commonly performed plastic surgery procedures to treat symptomatic macromasty or to correct asymmetry. Occult breast carcinomas were rarely defined in RM specimens. There are few studies aiming to define the incidence of non-proliferative and precancerous lesions.
We evaluated the pathological findings of the RM specimens that have been submitted to our Center for the last 6 years (2005-2011).
A total of 273 cases with bilateral RM were enrolled to the study. Of them, 229 cases had pathological changes. Eight cases (2.9%) had atypical ductal/lobular hyperplasia. One case (0.3%) had lobular carcinoma in situ; however, no invasive breast carcinoma was detected. Other pathological findings included fibrocystic changes, fibrosis, adenosis, fibroadenoma (without complex features), mastitis and duct ectasia.
Pathological examination of the RM specimens is quite important to define the lesions precancerous of breast carcinoma. Unknown occult breast lesions could be identified and early interventions may be taken into account.
缩乳术（RM）是治疗有症状的巨乳症或矫正乳房不对称的最常见的整形手术之一。隐匿性乳腺癌在 RM 标本中很少被定义。很少有研究旨在定义非增生性和癌前病变的发病率。
我们评估了过去 6 年来（2005-2011 年）提交给我们中心的 RM 标本的病理发现。
共有 273 例双侧 RM 病例纳入研究。其中，229 例有病理改变。8 例（2.9%）有非典型导管/小叶增生。1 例（0.3%）有小叶原位癌；然而，没有检测到浸润性乳腺癌。其他病理发现包括纤维囊性改变、纤维化、腺病、纤维腺瘤（无复杂特征）、乳腺炎和导管扩张。
RM 标本的病理检查对于定义乳腺癌前病变非常重要。可以识别未知的隐匿性乳腺病变，并考虑早期干预。
